NR4A2 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use NR4A2-specific vectors and viral particles designed for reliable NR4A2 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including NR4A2 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human NR4A2 Gene Overview
| Gene Name | nuclear receptor subfamily 4 group A member 2 |
|---|---|
| Gene Symbol | NR4A2 |
| Synonyms | NOT,RNR1,HZF-3,IDLDP,NURR1,TINUR |
| NCBI ID | 4929 |
| Ensembl ID | ENSG00000153234 |
| Uniprot ID | P43354 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Human NR4A2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC232142 | View Product |
| AAV Vector & Virus | Long-term expression | VC132142 | View Product |
| Adenovirus | Transient expression | A132142 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG132142 | View Product |
| Gene knockout (non-viral) | PG132142 | View Product | |
| Gene knockout (AAV) | VG132142 | View Product | |
| CRISPR Activation | Gene activation | LA132142 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS132142 | View Product |
| Gene knockdown (AAV) | VS132142 | View Product | |
| ORF Vector | Template DNA | PC132142 | View Product |
Mouse Nr4a2 Gene Overview
| Gene Name | nuclear receptor subfamily 4, group A, member 2 |
|---|---|
| Gene Symbol | Nr4a2 |
| Synonyms | NOT,HZF-3,Nurr1,RNR-1,TINOR,TINUR |
| NCBI ID | 18227 |
| Ensembl ID | ENSMUSG00000026826 |
| Uniprot ID | Q06219 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; nuclear glucocorticoid receptor binding activity; and protein heterodimerization activity. Involved in several processes, including cellular response to corticotropin-releasing hormone stimulus; dopaminergic neuron differentiation; and fat cell differentiation. Acts upstream of or within several processes, including dopamine biosynthetic process; nervous system development; and regulation of primary metabolic process. Located in nucleus. Is expressed in several structures, including ear; endocrine gland; genitourinary system; integumental system; and nervous system. Used to study Parkinson's disease and schizophrenia. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human NR4A2 (nuclear receptor subfamily 4 group A member 2). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Nr4a2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC432142 | View Product |
| Stable overexpression | LC532142 | View Product | |
| AAV Vector & Virus | Long-term expression | VC432142 | View Product |
| Long-term expression | VC532142 | View Product | |
| Adenovirus | Transient expression | A432142 | View Product |
| Transient expression | A532142 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG432142 | View Product |
| Gene knockout (non-viral) | PG432142 | View Product | |
| Gene knockout (AAV) | VG432142 | View Product | |
| CRISPR Activation | Gene activation | LA432142 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS432142 | View Product |
| Gene knockdown (AAV) | VS432142 | View Product | |
| ORF Vector | Template DNA | PC432142 | View Product |
| Template DNA | PC532142 | View Product |
Rat Nr4a2 Gene Overview
| Gene Name | nuclear receptor subfamily 4, group A, member 2 |
|---|---|
| Gene Symbol | Nr4a2 |
| Synonyms | RNR1,Nurr1 |
| NCBI ID | 54278 |
| Ensembl ID | ENSRNOG00000005600 |
| Uniprot ID | Q07917 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of neuron apoptotic process; positive regulation of transcription by RNA polymerase II; and retina development in camera-type eye. Acts upstream of or within response to insecticide. Located in chromatin. Biomarker of Parkinsonism and epilepsy. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human NR4A2 (nuclear receptor subfamily 4 group A member 2). [provided by Alliance of Genome Resources, Jul 2025]
Rat Nr4a2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC632142 | View Product |
| AAV Vector & Virus | Long-term expression | VC632142 | View Product |
| Adenovirus | Transient expression | A632142 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG632142 | View Product |
| Gene knockout (non-viral) | PG632142 | View Product | |
| Gene knockout (AAV) | VG632142 | View Product | |
| CRISPR Activation | Gene activation | LA632142 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS632142 | View Product |
| Gene knockdown (AAV) | VS632142 | View Product | |
| ORF Vector | Template DNA | PC632142 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |