NT5E Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use NT5E-specific vectors and viral particles designed for reliable NT5E overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including NT5E CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human NT5E Gene Overview
| Gene Name | 5'-nucleotidase ecto |
|---|---|
| Gene Symbol | NT5E |
| Synonyms | NT,eN,NT5,NTE,eNT,CD73,E5NT,CALJA |
| NCBI ID | 4907 |
| Ensembl ID | ENSG00000135318 |
| Uniprot ID | P21589 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
Human NT5E Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC132232 | View Product |
| AAV Vector & Virus | Long-term expression | VC132232 | View Product |
| Adenovirus | Transient expression | A132232 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG132232 | View Product |
| Gene knockout (non-viral) | PG132232 | View Product | |
| Gene knockout (AAV) | VG132232 | View Product | |
| CRISPR Activation | Gene activation | LA132232 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS132232 | View Product |
| Gene knockdown (AAV) | VS132232 | View Product | |
| ORF Vector | Template DNA | PC132232 | View Product |
Mouse Nt5e Gene Overview
| Gene Name | 5' nucleotidase, ecto |
|---|---|
| Gene Symbol | Nt5e |
| Synonyms | NT,Nt5,eNT,CD73,5'-NT,2210401F01Rik |
| NCBI ID | 23959 |
| Ensembl ID | ENSMUSG00000032420 |
| Uniprot ID | Q61503 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a membrane-bound nucleotidase that hydrolyzes extracellular nucleoside monophosphates. The encoded preproprotein undergoes proteolytic processing to generate to a functional, homodimeric enzyme that preferentially uses adenosine monophosphate as a substrate to generate free adenosine. Mice lacking the encoded protein exhibit a significantly reduced fall in stop flow pressure and superficial nephron glomerular filtration rate in response to a saturating increase of tubular perfusion flow. [provided by RefSeq, Sep 2016]
Mouse Nt5e Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC432232 | View Product |
| AAV Vector & Virus | Long-term expression | VC432232 | View Product |
| Adenovirus | Transient expression | A432232 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG432232 | View Product |
| Gene knockout (non-viral) | PG432232 | View Product | |
| Gene knockout (AAV) | VG432232 | View Product | |
| CRISPR Activation | Gene activation | LA432232 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS432232 | View Product |
| Gene knockdown (AAV) | VS432232 | View Product | |
| ORF Vector | Template DNA | PC432232 | View Product |
Rat Nt5e Gene Overview
| Gene Name | 5' nucleotidase, ecto |
|---|---|
| Gene Symbol | Nt5e |
| Synonyms | Nt5,CD73 |
| NCBI ID | 58813 |
| Ensembl ID | ENSRNOG00000011071 |
| Uniprot ID | P21588 |
| Gene Type | Protein coding |
Gene Summary
Enables 5'-nucleotidase activity and ferrous iron binding activity. Involved in nucleobase-containing small molecule metabolic process; positive regulation of lipid biosynthetic process; and response to aluminum ion. Located in cell surface and synaptic membrane. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in hereditary arterial and articular multiple calcification syndrome. Orthologous to human NT5E (5'-nucleotidase ecto). [provided by Alliance of Genome Resources, Jul 2025]
Rat Nt5e Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC632232 | View Product |
| AAV Vector & Virus | Long-term expression | VC632232 | View Product |
| Adenovirus | Transient expression | A632232 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG632232 | View Product |
| Gene knockout (non-viral) | PG632232 | View Product | |
| Gene knockout (AAV) | VG632232 | View Product | |
| CRISPR Activation | Gene activation | LA632232 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS632232 | View Product |
| Gene knockdown (AAV) | VS632232 | View Product | |
| ORF Vector | Template DNA | PC632232 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |