OLIG2 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use OLIG2-specific vectors and viral particles designed for reliable OLIG2 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including OLIG2 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human OLIG2 Gene Overview
| Gene Name | oligodendrocyte transcription factor 2 |
|---|---|
| Gene Symbol | OLIG2 |
| Synonyms | BHLHB1,OLIGO2,RACK17,PRKCBP2,bHLHe19 |
| NCBI ID | 10215 |
| Ensembl ID | ENSG00000205927 |
| Uniprot ID | Q13516 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]
Human OLIG2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC133612 | View Product |
| AAV Vector & Virus | Long-term expression | VC133612 | View Product |
| Adenovirus | Transient expression | A133612 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG133612 | View Product |
| Gene knockout (non-viral) | PG133612 | View Product | |
| Gene knockout (AAV) | VG133612 | View Product | |
| CRISPR Activation | Gene activation | LA133612 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS133612 | View Product |
| Gene knockdown (AAV) | VS133612 | View Product | |
| ORF Vector | Template DNA | PC133612 | View Product |
Mouse Olig2 Gene Overview
| Gene Name | oligodendrocyte transcription factor 2 |
|---|---|
| Gene Symbol | Olig2 |
| Synonyms | RK17,Olg-2,Bhlhb1,Oligo2,bHLHe19 |
| NCBI ID | 50913 |
| Ensembl ID | ENSMUSG00000039830 |
| Uniprot ID | Q9EQW6 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; HMG box domain binding activity; and identical protein binding activity. Acts upstream of or within several processes, including negative regulation of transcription by RNA polymerase II; nervous system development; and positive regulation of oligodendrocyte differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; epidermis; future brain; genitourinary system; and sensory organ. Orthologous to human OLIG2 (oligodendrocyte transcription factor 2). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Olig2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC433612 | View Product |
| AAV Vector & Virus | Long-term expression | VC433612 | View Product |
| Adenovirus | Transient expression | A433612 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG433612 | View Product |
| Gene knockout (non-viral) | PG433612 | View Product | |
| Gene knockout (AAV) | VG433612 | View Product | |
| CRISPR Activation | Gene activation | LA433612 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS433612 | View Product |
| Gene knockdown (AAV) | VS433612 | View Product | |
| ORF Vector | Template DNA | PC433612 | View Product |
Rat Olig2 Gene Overview
| Gene Name | oligodendrocyte transcription factor 2 |
|---|---|
| Gene Symbol | Olig2 |
| Synonyms | |
| NCBI ID | 304103 |
| Ensembl ID | ENSRNOG00000028658 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including E-box binding activity; HMG box domain binding activity; and identical protein binding activity. Involved in oligodendrocyte differentiation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Biomarker of status epilepticus. Orthologous to human OLIG2 (oligodendrocyte transcription factor 2). [provided by Alliance of Genome Resources, Jul 2025]
Rat Olig2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC633612 | View Product |
| AAV Vector & Virus | Long-term expression | VC633612 | View Product |
| Adenovirus | Transient expression | A633612 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG633612 | View Product |
| Gene knockout (non-viral) | PG633612 | View Product | |
| Gene knockout (AAV) | VG633612 | View Product | |
| CRISPR Activation | Gene activation | LA633612 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS633612 | View Product |
| Gene knockdown (AAV) | VS633612 | View Product | |
| ORF Vector | Template DNA | PC633612 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |