PARG Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use PARG-specific vectors and viral particles designed for reliable PARG overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including PARG CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human PARG Gene Overview
| Gene Name | poly(ADP-ribose) glycohydrolase |
|---|---|
| Gene Symbol | PARG |
| Synonyms | PARG99 |
| NCBI ID | 8505 |
| Ensembl ID | ENSG00000227345 |
| Uniprot ID | Q86W56 |
| Gene Type | Protein coding |
Gene Summary
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
Human PARG Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC136011 | View Product |
| AAV Vector & Virus | Long-term expression | VC136011 | View Product |
| Adenovirus | Transient expression | A136011 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG136011 | View Product |
| Gene knockout (non-viral) | PG136011 | View Product | |
| Gene knockout (AAV) | VG136011 | View Product | |
| CRISPR Activation | Gene activation | LA136011 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS136011 | View Product |
| Gene knockdown (AAV) | VS136011 | View Product | |
| ORF Vector | Template DNA | PC136011 | View Product |
Mouse Parg Gene Overview
| Gene Name | poly (ADP-ribose) glycohydrolase |
|---|---|
| Gene Symbol | Parg |
| Synonyms | |
| NCBI ID | 26430 |
| Ensembl ID | ENSMUSG00000021911 |
| Uniprot ID | O88622 |
| Gene Type | Protein coding |
Gene Summary
Enables poly(ADP-ribose) glycohydrolase activity. Acts upstream of or within DNA damage response and detection of bacterium. Located in cytosol and nucleus. Is expressed in several structures, including adrenal gland; brain; cardiovascular system; genitourinary system; and gut. Orthologous to human PARG (poly(ADP-ribose) glycohydrolase). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Parg Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC436011 | View Product |
| AAV Vector & Virus | Long-term expression | VC436011 | View Product |
| Adenovirus | Transient expression | A436011 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG436011 | View Product |
| Gene knockout (non-viral) | PG436011 | View Product | |
| Gene knockout (AAV) | VG436011 | View Product | |
| CRISPR Activation | Gene activation | LA436011 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS436011 | View Product |
| Gene knockdown (AAV) | VS436011 | View Product | |
| ORF Vector | Template DNA | PC436011 | View Product |
Rat Parg Gene Overview
| Gene Name | poly (ADP-ribose) glycohydrolase |
|---|---|
| Gene Symbol | Parg |
| Synonyms | |
| NCBI ID | 83507 |
| Ensembl ID | ENSRNOG00000019978 |
| Uniprot ID | Q9QYM2 |
| Gene Type | Protein coding |
Gene Summary
Enables chromatin binding activity and poly(ADP-ribose) glycohydrolase activity. Involved in positive regulation of DNA repair. Located in chromatin. Used to study brain infarction. Biomarker of borna disease. Orthologous to human PARG (poly(ADP-ribose) glycohydrolase). [provided by Alliance of Genome Resources, Jul 2025]
Rat Parg Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC636011 | View Product |
| AAV Vector & Virus | Long-term expression | VC636011 | View Product |
| Adenovirus | Transient expression | A636011 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG636011 | View Product |
| Gene knockout (non-viral) | PG636011 | View Product | |
| Gene knockout (AAV) | VG636011 | View Product | |
| CRISPR Activation | Gene activation | LA636011 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS636011 | View Product |
| Gene knockdown (AAV) | VS636011 | View Product | |
| ORF Vector | Template DNA | PC636011 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |