PIEZO2 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use PIEZO2-specific vectors and viral particles designed for reliable PIEZO2 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including PIEZO2 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human PIEZO2 Gene Overview
| Gene Name | piezo type mechanosensitive ion channel component 2 |
|---|---|
| Gene Symbol | PIEZO2 |
| Synonyms | DA3,DA5,MWKS,DAIPT,FAM38B,HsT748,HsT771,FAM38B2,C18orf30,C18orf58 |
| NCBI ID | 63895 |
| Ensembl ID | ENSG00000154864 |
| Uniprot ID | Q9H5I5 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
Human PIEZO2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG120015 | View Product |
| Gene knockout (non-viral) | PG120015 | View Product | |
| Gene knockout (AAV) | VG120015 | View Product | |
| CRISPR Activation | Gene activation | LA120015 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS120015 | View Product |
| Gene knockdown (AAV) | VS120015 | View Product |
Mouse Piezo2 Gene Overview
| Gene Name | piezo-type mechanosensitive ion channel component 2 |
|---|---|
| Gene Symbol | Piezo2 |
| Synonyms | Fam38b,Fam38b2,5930434P17,9030411M15Rik,9430028L06Rik |
| NCBI ID | 667742 |
| Ensembl ID | ENSMUSG00000041482 |
| Uniprot ID | Q8CD54 |
| Gene Type | Protein coding |
Gene Summary
Enables mechanosensitive monoatomic ion channel activity and monoatomic cation channel activity. Involved in detection of mechanical stimulus involved in sensory perception and monoatomic cation transport. Acts upstream of or within regulation of membrane potential. Located in cuticular plate; neuronal cell body membrane; and stereocilium. Is expressed in dorsal root ganglion; forelimb; lung; lung epithelium; and thoracic dorsal root ganglion. Human ortholog(s) of this gene implicated in distal arthrogryposis type 3 and distal arthrogryposis type 5. Orthologous to human PIEZO2 (piezo type mechanosensitive ion channel component 2). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Piezo2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|
Rat Piezo2 Gene Overview
| Gene Name | piezo-type mechanosensitive ion channel component 2 |
|---|---|
| Gene Symbol | Piezo2 |
| Synonyms | Fam38b,RGD1306866 |
| NCBI ID | 307380 |
| Ensembl ID | ENSRNOG00000038784 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable mechanosensitive monoatomic ion channel activity and monoatomic cation channel activity. Predicted to be involved in several processes, including cellular response to mechanical stimulus; detection of mechanical stimulus involved in sensory perception; and monoatomic cation transport. Predicted to be located in cuticular plate; neuronal cell body membrane; and stereocilium. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 3 and distal arthrogryposis type 5. Orthologous to human PIEZO2 (piezo type mechanosensitive ion channel component 2). [provided by Alliance of Genome Resources, Jul 2025]
Rat Piezo2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |