PIM1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use PIM1-specific vectors and viral particles designed for reliable PIM1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including PIM1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human PIM1 Gene Overview
| Gene Name | Pim-1 proto-oncogene, serine/threonine kinase |
|---|---|
| Gene Symbol | PIM1 |
| Synonyms | PIM |
| NCBI ID | 5292 |
| Ensembl ID | ENSG00000137193 |
| Uniprot ID | P11309 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
Human PIM1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC136696 | View Product |
| AAV Vector & Virus | Long-term expression | VC136696 | View Product |
| Adenovirus | Transient expression | A136696 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG136696 | View Product |
| Gene knockout (non-viral) | PG136696 | View Product | |
| Gene knockout (AAV) | VG136696 | View Product | |
| CRISPR Activation | Gene activation | LA136696 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS136696 | View Product |
| Gene knockdown (AAV) | VS136696 | View Product | |
| ORF Vector | Template DNA | PC136696 | View Product |
Mouse Pim1 Gene Overview
| Gene Name | Pim1, proto-oncogene, serine/threonine kinase |
|---|---|
| Gene Symbol | Pim1 |
| Synonyms | Pim-1 |
| NCBI ID | 18712 |
| Ensembl ID | ENSMUSG00000024014 |
| Uniprot ID | P06803 |
| Gene Type | Protein coding |
Gene Summary
Enables ATP binding activity; manganese ion binding activity; and protein serine/threonine kinase activity. Involved in several processes, including positive regulation of brown fat cell differentiation; protein stabilization; and regulation of hematopoietic stem cell proliferation. Predicted to be located in cytosol; nuclear lumen; and plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; genitourinary system; primitive streak; sensory organ; and yolk sac. Orthologous to human PIM1 (Pim-1 proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Pim1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC436696 | View Product |
| AAV Vector & Virus | Long-term expression | VC436696 | View Product |
| Adenovirus | Transient expression | A436696 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG436696 | View Product |
| Gene knockout (non-viral) | PG436696 | View Product | |
| Gene knockout (AAV) | VG436696 | View Product | |
| CRISPR Activation | Gene activation | LA436696 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS436696 | View Product |
| Gene knockdown (AAV) | VS436696 | View Product | |
| ORF Vector | Template DNA | PC436696 | View Product |
Rat Pim1 Gene Overview
| Gene Name | Pim-1 proto-oncogene, serine/threonine kinase |
|---|---|
| Gene Symbol | Pim1 |
| Synonyms | |
| NCBI ID | 24649 |
| Ensembl ID | ENSRNOG00000000529 |
| Uniprot ID | P26794 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including ATP binding activity; manganese ion binding activity; and ribosomal small subunit binding activity. Predicted to be involved in several processes, including positive regulation of TORC1 signaling; positive regulation of cell population proliferation; and regulation of DNA-templated transcription. Predicted to be located in cytosol; nuclear lumen; and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human PIM1 (Pim-1 proto-oncogene, serine/threonine kinase). [provided by Alliance of Genome Resources, Apr 2025]
Rat Pim1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC636696 | View Product |
| AAV Vector & Virus | Long-term expression | VC636696 | View Product |
| Adenovirus | Transient expression | A636696 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG636696 | View Product |
| Gene knockout (non-viral) | PG636696 | View Product | |
| Gene knockout (AAV) | VG636696 | View Product | |
| CRISPR Activation | Gene activation | LA636696 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS636696 | View Product |
| Gene knockdown (AAV) | VS636696 | View Product | |
| ORF Vector | Template DNA | PC636696 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |