PINK1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use PINK1-specific vectors and viral particles designed for reliable PINK1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including PINK1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human PINK1 Gene Overview
| Gene Name | PTEN induced kinase 1 |
|---|---|
| Gene Symbol | PINK1 |
| Synonyms | BRPK,PARK6 |
| NCBI ID | 65018 |
| Ensembl ID | ENSG00000158828 |
| Uniprot ID | Q9BXM7 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008]
Human PINK1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC125584 | View Product |
| AAV Vector & Virus | Long-term expression | VC125584 | View Product |
| Adenovirus | Transient expression | A125584 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG136703 | View Product |
| Gene knockout (non-viral) | PG136703 | View Product | |
| Gene knockout (AAV) | VG136703 | View Product | |
| CRISPR Activation | Gene activation | LA136703 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS136703 | View Product |
| Gene knockdown (AAV) | VS136703 | View Product | |
| ORF Vector | Template DNA | PC125584 | View Product |
Mouse Pink1 Gene Overview
| Gene Name | PTEN induced putative kinase 1 |
|---|---|
| Gene Symbol | Pink1 |
| Synonyms | BRPK,mFLJ00387,1190006F07Rik |
| NCBI ID | 68943 |
| Ensembl ID | ENSMUSG00000028756 |
| Uniprot ID | Q99MQ3 |
| Gene Type | Protein coding |
Gene Summary
Enables ATP binding activity; magnesium ion binding activity; and protein kinase activity. Involved in several processes, including negative regulation of apoptotic process; protein stabilization; and regulation of gene expression. Acts upstream of or within positive regulation of dopamine secretion; positive regulation of dopaminergic synaptic transmission; and positive regulation of mitochondrial electron transport, NADH to ubiquinone. Located in endoplasmic reticulum and mitochondrial inner membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Used to study Parkinson's disease 6. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 6. Orthologous to human PINK1 (PTEN induced kinase 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Pink1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC436703 | View Product |
| AAV Vector & Virus | Long-term expression | VC436703 | View Product |
| Adenovirus | Transient expression | A436703 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG436703 | View Product |
| Gene knockout (non-viral) | PG436703 | View Product | |
| Gene knockout (AAV) | VG436703 | View Product | |
| CRISPR Activation | Gene activation | LA436703 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS436703 | View Product |
| Gene knockdown (AAV) | VS436703 | View Product | |
| ORF Vector | Template DNA | PC436703 | View Product |
Rat Pink1 Gene Overview
| Gene Name | PTEN induced kinase 1 |
|---|---|
| Gene Symbol | Pink1 |
| Synonyms | |
| NCBI ID | 298575 |
| Ensembl ID | ENSRNOG00000015385 |
| Uniprot ID | B5DFG1 |
| Gene Type | Protein coding |
Gene Summary
Enables protein serine/threonine kinase activity and ubiquitin protein ligase binding activity. Involved in several processes, including cellular response to hydrogen sulfide; positive regulation of mitochondrial fission; and regulation of signal transduction. Located in endoplasmic reticulum; growth cone; and mitochondrial envelope. Used to study Parkinson's disease and Parkinsonism. Biomarker of metabolic dysfunction-associated steatohepatitis. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 6. Orthologous to human PINK1 (PTEN induced kinase 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Pink1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC636703 | View Product |
| Stable overexpression | LC645094 | View Product | |
| AAV Vector & Virus | Long-term expression | VC636703 | View Product |
| Adenovirus | Transient expression | A636703 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG736703 | View Product |
| Gene knockout (non-viral) | PG736703 | View Product | |
| Gene knockout (AAV) | VG636703 | View Product | |
| CRISPR Activation | Gene activation | LA636703 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS636703 | View Product |
| Gene knockdown (Lentiviral) | LS645094 | View Product | |
| Gene knockdown (AAV) | VS636703 | View Product | |
| ORF Vector | Template DNA | PC636703 | View Product |
| Template DNA | PC645094 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |