POSTN Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use POSTN-specific vectors and viral particles designed for reliable POSTN overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including POSTN CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human POSTN Gene Overview
| Gene Name | periostin |
|---|---|
| Gene Symbol | POSTN |
| Synonyms | PN,OSF2,OSF-2,PDLPOSTN |
| NCBI ID | 10631 |
| Ensembl ID | ENSG00000133110 |
| Uniprot ID | Q15063 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
Human POSTN Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC125947 | View Product |
| Stable overexpression | LC125948 | View Product | |
| Stable overexpression | LC137238 | View Product | |
| AAV Vector & Virus | Long-term expression | VC125947 | View Product |
| Long-term expression | VC125948 | View Product | |
| Long-term expression | VC137238 | View Product | |
| Adenovirus | Transient expression | A125947 | View Product |
| Transient expression | A125948 | View Product | |
| Transient expression | A137238 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG137238 | View Product |
| Gene knockout (non-viral) | PG137238 | View Product | |
| Gene knockout (AAV) | VG137238 | View Product | |
| CRISPR Activation | Gene activation | LA137238 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS137238 | View Product |
| Gene knockdown (AAV) | VS137238 | View Product | |
| ORF Vector | Template DNA | PC125947 | View Product |
| Template DNA | PC125948 | View Product | |
| Template DNA | PC137238 | View Product |
Mouse Postn Gene Overview
| Gene Name | periostin, osteoblast specific factor |
|---|---|
| Gene Symbol | Postn |
| Synonyms | PN,PLF,Osf2,OSF-2,A630052E07Rik |
| NCBI ID | 50706 |
| Ensembl ID | ENSMUSG00000027750 |
| Uniprot ID | Q62009 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
Mouse Postn Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC437238 | View Product |
| Stable overexpression | LC537238 | View Product | |
| AAV Vector & Virus | Long-term expression | VC437238 | View Product |
| Adenovirus | Transient expression | A437238 | View Product |
| Transient expression | A537238 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG437238 | View Product |
| Gene knockout (non-viral) | PG437238 | View Product | |
| Gene knockout (AAV) | VG437238 | View Product | |
| CRISPR Activation | Gene activation | LA437238 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS437238 | View Product |
| Gene knockdown (AAV) | VS437238 | View Product | |
| ORF Vector | Template DNA | PC437238 | View Product |
| Template DNA | PC537238 | View Product |
Rat Postn Gene Overview
| Gene Name | periostin |
|---|---|
| Gene Symbol | Postn |
| Synonyms | Plf |
| NCBI ID | 361945 |
| Ensembl ID | ENSRNOG00000012660 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable cell adhesion molecule binding activity; heparin binding activity; and metal ion binding activity. Involved in several processes, including bone regeneration; negative regulation of cell-substrate adhesion; and positive regulation of chemokine (C-X-C motif) ligand 2 production. Located in extracellular space and neuromuscular junction. Used to study congestive heart failure. Biomarker of artery disease (multiple); degenerative disc disease; end stage renal disease; periodontitis; and tendinitis. Orthologous to human POSTN (periostin). [provided by Alliance of Genome Resources, Jul 2025]
Rat Postn Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC637238 | View Product |
| AAV Vector & Virus | Long-term expression | VC637238 | View Product |
| Adenovirus | Transient expression | A637238 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG637238 | View Product |
| Gene knockout (non-viral) | PG637238 | View Product | |
| Gene knockout (AAV) | VG637238 | View Product | |
| CRISPR Activation | Gene activation | LA637238 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS637238 | View Product |
| Gene knockdown (AAV) | VS637238 | View Product | |
| ORF Vector | Template DNA | PC637238 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |