PPP2CA Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use PPP2CA-specific vectors and viral particles designed for reliable PPP2CA overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including PPP2CA CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human PPP2CA Gene Overview
| Gene Name | protein phosphatase 2 catalytic subunit alpha |
|---|---|
| Gene Symbol | PPP2CA |
| Synonyms | HJS3,RP-C,PP2Ac,PP2CA,NEDLBA,PP2Calpha |
| NCBI ID | 5515 |
| Ensembl ID | ENSG00000113575 |
| Uniprot ID | P67775 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008]
Human PPP2CA Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC137466 | View Product |
| AAV Vector & Virus | Long-term expression | VC137466 | View Product |
| Adenovirus | Transient expression | A137466 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG137466 | View Product |
| Gene knockout (non-viral) | PG137466 | View Product | |
| Gene knockout (AAV) | VG137466 | View Product | |
| CRISPR Activation | Gene activation | LA137466 | View Product |
| siRNA Tools | Gene knockdown (AAV) | VS137466 | View Product |
| ORF Vector | Template DNA | PC137466 | View Product |
Mouse Ppp2ca Gene Overview
| Gene Name | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform |
|---|---|
| Gene Symbol | Ppp2ca |
| Synonyms | PP2A |
| NCBI ID | 19052 |
| Ensembl ID | ENSMUSG00000020349 |
| Uniprot ID | P63330 |
| Gene Type | Protein coding |
Gene Summary
Enables GABA receptor binding activity and protein serine/threonine phosphatase activity. Involved in T cell homeostasis; negative regulation of glycolytic process through fructose-6-phosphate; and regulation of intracellular signal transduction. Acts upstream of or within mesoderm development. Located in chromosome, centromeric region; cytosol; and plasma membrane. Part of protein phosphatase type 2A complex. Is active in synapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PPP2CA (protein phosphatase 2 catalytic subunit alpha). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Ppp2ca Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC437466 | View Product |
| AAV Vector & Virus | Long-term expression | VC437466 | View Product |
| Adenovirus | Transient expression | A437466 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG437466 | View Product |
| Gene knockout (non-viral) | PG437466 | View Product | |
| Gene knockout (AAV) | VG437466 | View Product | |
| CRISPR Activation | Gene activation | LA437466 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS437466 | View Product |
| Gene knockdown (AAV) | VS437466 | View Product | |
| ORF Vector | Template DNA | PC437466 | View Product |
Rat Ppp2ca Gene Overview
| Gene Name | protein phosphatase 2 catalytic subunit alpha |
|---|---|
| Gene Symbol | Ppp2ca |
| Synonyms | PP2A,Pp2a1 |
| NCBI ID | 24672 |
| Ensembl ID | |
| Uniprot ID | P63331 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including beta-2 adrenergic receptor binding activity; enzyme binding activity; and protein antigen binding activity. Involved in several processes, including cellular response to ethanol; negative regulation of transport; and regulation of phosphate metabolic process. Acts upstream of or within regulation of protein autophosphorylation; regulation of protein catabolic process; and regulation of signaling receptor activity. Located in terminal bouton. Part of protein phosphatase type 2A complex. Biomarker of type 2 diabetes mellitus. Orthologous to human PPP2CA (protein phosphatase 2 catalytic subunit alpha). [provided by Alliance of Genome Resources, Jul 2025]
Rat Ppp2ca Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC637466 | View Product |
| AAV Vector & Virus | Long-term expression | VC637466 | View Product |
| Adenovirus | Transient expression | A637466 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG637466 | View Product |
| Gene knockout (non-viral) | PG637466 | View Product | |
| Gene knockout (AAV) | VG637466 | View Product | |
| CRISPR Activation | Gene activation | LA637466 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS637466 | View Product |
| Gene knockdown (AAV) | VS637466 | View Product | |
| ORF Vector | Template DNA | PC637466 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |