PROM1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use PROM1-specific vectors and viral particles designed for reliable PROM1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including PROM1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human PROM1 Gene Overview
| Gene Name | prominin 1 |
|---|---|
| Gene Symbol | PROM1 |
| Synonyms | RP41,AC133,CD133,MCDR2,STGD4,CORD12,PROML1,MSTP061 |
| NCBI ID | 8842 |
| Ensembl ID | ENSG00000007062 |
| Uniprot ID | O43490 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Human PROM1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC137737 | View Product |
| AAV Vector & Virus | Long-term expression | VC137737 | View Product |
| Adenovirus | Transient expression | A137737 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG137737 | View Product |
| Gene knockout (non-viral) | PG137737 | View Product | |
| Gene knockout (AAV) | VG137737 | View Product | |
| CRISPR Activation | Gene activation | LA137737 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS137737 | View Product |
| Gene knockdown (AAV) | VS137737 | View Product | |
| ORF Vector | Template DNA | PC137737 | View Product |
Mouse Prom1 Gene Overview
| Gene Name | prominin 1 |
|---|---|
| Gene Symbol | Prom1 |
| Synonyms | Prom,AC133,CD133,Prom-1,Proml1,4932416E19Rik |
| NCBI ID | 19126 |
| Ensembl ID | ENSMUSG00000029086 |
| Uniprot ID | O54990 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable actinin binding activity; cadherin binding activity; and cholesterol binding activity. Involved in camera-type eye photoreceptor cell differentiation and retina layer formation. Located in several cellular components, including brush border; photoreceptor outer segment; and prominosome. Is expressed in several structures, including brain; eye; genitourinary system; intestine; and neural ectoderm. Used to study retinitis pigmentosa 41. Human ortholog(s) of this gene implicated in cone-rod dystrophy 12; retinal macular dystrophy 2; and retinitis pigmentosa 41. Orthologous to human PROM1 (prominin 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Prom1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC437737 | View Product |
| Stable overexpression | LC537737 | View Product | |
| AAV Vector & Virus | Long-term expression | VC437737 | View Product |
| Long-term expression | VC537737 | View Product | |
| Adenovirus | Transient expression | A437737 | View Product |
| Transient expression | A537737 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG437737 | View Product |
| Gene knockout (non-viral) | PG437737 | View Product | |
| Gene knockout (AAV) | VG437737 | View Product | |
| CRISPR Activation | Gene activation | LA437737 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS437737 | View Product |
| Gene knockdown (AAV) | VS437737 | View Product | |
| ORF Vector | Template DNA | PC437737 | View Product |
| Template DNA | PC537737 | View Product |
Rat Prom1 Gene Overview
| Gene Name | prominin 1 |
|---|---|
| Gene Symbol | Prom1 |
| Synonyms | Prom,CD133 |
| NCBI ID | 60357 |
| Ensembl ID | ENSRNOG00000003098 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable actinin binding activity; cadherin binding activity; and cholesterol binding activity. Predicted to be involved in several processes, including glomerular epithelial cell differentiation; photoreceptor cell maintenance; and retina morphogenesis in camera-type eye. Predicted to be located in several cellular components, including endoplasmic reticulum-Golgi intermediate compartment; extracellular exosome; and photoreceptor outer segment membrane. Predicted to be active in several cellular components, including apical plasma membrane; microvillus; and prominosome. Used to study diabetes mellitus. Human ortholog(s) of this gene implicated in cone-rod dystrophy 12; retinal macular dystrophy 2; and retinitis pigmentosa 41. Orthologous to human PROM1 (prominin 1). [provided by Alliance of Genome Resources, Apr 2025]
Rat Prom1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC637737 | View Product |
| Stable overexpression | LC737737 | View Product | |
| AAV Vector & Virus | Long-term expression | VC737737 | View Product |
| Adenovirus | Transient expression | A637737 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG637737 | View Product |
| Gene knockout (non-viral) | PG637737 | View Product | |
| Gene knockout (AAV) | VG637737 | View Product | |
| CRISPR Activation | Gene activation | LA637737 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS637737 | View Product |
| Gene knockdown (AAV) | VS637737 | View Product | |
| ORF Vector | Template DNA | PC637737 | View Product |
| Template DNA | PC737737 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |