PTPRA Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use PTPRA-specific vectors and viral particles designed for reliable PTPRA overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including PTPRA CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human PTPRA Gene Overview
| Gene Name | protein tyrosine phosphatase receptor type A |
|---|---|
| Gene Symbol | PTPRA |
| Synonyms | LRP,HLPR,PTPA,HEPTP,HPTPA,RPTPA,PTPRL2,HPTPalpha,R-PTP-alpha |
| NCBI ID | 5786 |
| Ensembl ID | ENSG00000132670 |
| Uniprot ID | P18433 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
Human PTPRA Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC138168 | View Product |
| AAV Vector & Virus | Long-term expression | VC138168 | View Product |
| Adenovirus | Transient expression | A138168 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG138168 | View Product |
| Gene knockout (non-viral) | PG138168 | View Product | |
| Gene knockout (AAV) | VG138168 | View Product | |
| CRISPR Activation | Gene activation | LA138168 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS138168 | View Product |
| Gene knockdown (AAV) | VS138168 | View Product | |
| ORF Vector | Template DNA | PC138168 | View Product |
Mouse Ptpra Gene Overview
| Gene Name | protein tyrosine phosphatase receptor type A |
|---|---|
| Gene Symbol | Ptpra |
| Synonyms | Ptpa,Rptra,Ptpalpha,Rptpalpha,Rptralpha |
| NCBI ID | 19262 |
| Ensembl ID | ENSMUSG00000027303 |
| Uniprot ID | P18052 |
| Gene Type | Protein coding |
Gene Summary
Enables protein tyrosine phosphatase activity. Involved in integrin-mediated signaling pathway; modulation of chemical synaptic transmission; and regulation of focal adhesion assembly. Acts upstream of or within insulin receptor signaling pathway and protein phosphorylation. Located in focal adhesion and membrane. Is active in Schaffer collateral - CA1 synapse and synaptic membrane. Is expressed in several structures, including adrenal gland; central nervous system; extraembryonic component; future brain; and genitourinary system. Orthologous to human PTPRA (protein tyrosine phosphatase receptor type A). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Ptpra Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC438168 | View Product |
| Stable overexpression | LC538168 | View Product | |
| AAV Vector & Virus | Long-term expression | VC438168 | View Product |
| Long-term expression | VC538168 | View Product | |
| Adenovirus | Transient expression | A438168 | View Product |
| Transient expression | A538168 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG438168 | View Product |
| Gene knockout (non-viral) | PG438168 | View Product | |
| Gene knockout (AAV) | VG438168 | View Product | |
| CRISPR Activation | Gene activation | LA438168 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS438168 | View Product |
| Gene knockdown (AAV) | VS438168 | View Product | |
| ORF Vector | Template DNA | PC438168 | View Product |
| Template DNA | PC538168 | View Product |
Rat Ptpra Gene Overview
| Gene Name | protein tyrosine phosphatase, receptor type, A |
|---|---|
| Gene Symbol | Ptpra |
| Synonyms | LRP |
| NCBI ID | 25167 |
| Ensembl ID | ENSRNOG00000021223 |
| Uniprot ID | Q03348 |
| Gene Type | Protein coding |
Gene Summary
Enables protein tyrosine phosphatase activity. Involved in oligodendrocyte differentiation and positive regulation of oligodendrocyte differentiation. Predicted to be located in focal adhesion and membrane. Predicted to be part of receptor complex. Predicted to be active in Schaffer collateral - CA1 synapse and synaptic membrane. Orthologous to human PTPRA (protein tyrosine phosphatase receptor type A). [provided by Alliance of Genome Resources, Jul 2025]
Rat Ptpra Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC638168 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG638168 | View Product |
| Gene knockout (non-viral) | PG638168 | View Product | |
| Gene knockout (AAV) | VG638168 | View Product | |
| CRISPR Activation | Gene activation | LA638168 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS638168 | View Product |
| Gene knockdown (AAV) | VS638168 | View Product | |
| ORF Vector | Template DNA | PC638168 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |