PTPRJ Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use PTPRJ-specific vectors and viral particles designed for reliable PTPRJ overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including PTPRJ CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human PTPRJ Gene Overview
| Gene Name | protein tyrosine phosphatase receptor type J |
|---|---|
| Gene Symbol | PTPRJ |
| Synonyms | DEP1,SCC1,CD148,THC10,HPTPeta,R-PTP-J,HPTP eta,R-PTP-ETA |
| NCBI ID | 5795 |
| Ensembl ID | ENSG00000149177 |
| Uniprot ID | Q12913 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Human PTPRJ Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC138177 | View Product |
| AAV Vector & Virus | Long-term expression | VC138177 | View Product |
| Adenovirus | Transient expression | A138177 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG138177 | View Product |
| Gene knockout (non-viral) | PG138177 | View Product | |
| Gene knockout (AAV) | VG138177 | View Product | |
| CRISPR Activation | Gene activation | LA138177 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS138177 | View Product |
| Gene knockdown (AAV) | VS138177 | View Product | |
| ORF Vector | Template DNA | PC138177 | View Product |
Mouse Ptprj Gene Overview
| Gene Name | protein tyrosine phosphatase receptor type J |
|---|---|
| Gene Symbol | Ptprj |
| Synonyms | BET,Byp,Scc1,CD148,DEP-1,Ptpb2,RPTPJ,Scc-1,R-PTP-J,PTPbeta2,R-PTP-eta |
| NCBI ID | 19271 |
| Ensembl ID | ENSMUSG00000025314 |
| Uniprot ID | Q64455 |
| Gene Type | Protein coding |
Gene Summary
Enables protein tyrosine phosphatase activity. Involved in several processes, including peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity; regulation of cell migration; and regulation of signal transduction. Acts upstream of or within heart development; oligodendrocyte differentiation; and vasculogenesis. Located in immunological synapse and ruffle membrane. Is expressed in midbrain; renal calyx; renal pelvis; and superior colliculus. Human ortholog(s) of this gene implicated in colorectal cancer; lung adenocarcinoma; lung squamous cell carcinoma; and thrombocytopenia. Orthologous to human PTPRJ (protein tyrosine phosphatase receptor type J). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Ptprj Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC438177 | View Product |
| Stable overexpression | LC538177 | View Product | |
| Adenovirus | Transient expression | A438177 | View Product |
| Transient expression | A538177 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG438177 | View Product |
| Gene knockout (non-viral) | PG438177 | View Product | |
| Gene knockout (AAV) | VG438177 | View Product | |
| CRISPR Activation | Gene activation | LA438177 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS438177 | View Product |
| Gene knockdown (AAV) | VS438177 | View Product | |
| ORF Vector | Template DNA | PC438177 | View Product |
| Template DNA | PC538177 | View Product |
Rat Ptprj Gene Overview
| Gene Name | protein tyrosine phosphatase, receptor type, J |
|---|---|
| Gene Symbol | Ptprj |
| Synonyms | DEP-1 |
| NCBI ID | 29645 |
| Ensembl ID | ENSRNOG00000034025 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including beta-catenin binding activity; delta-catenin binding activity; and gamma-catenin binding activity. Predicted to be involved in several processes, including hemopoiesis; regulation of cell migration; and regulation of signal transduction. Predicted to act upstream of or within heart development; oligodendrocyte differentiation; and vasculogenesis. Predicted to be located in several cellular components, including immunological synapse; nuclear lumen; and ruffle membrane. Used to study hypertension. Human ortholog(s) of this gene implicated in colorectal cancer; lung adenocarcinoma; lung squamous cell carcinoma; and thrombocytopenia. Orthologous to human PTPRJ (protein tyrosine phosphatase receptor type J). [provided by Alliance of Genome Resources, Jul 2025]
Rat Ptprj Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC638177 | View Product |
| siRNA Tools | Gene knockdown (AAV) | VS638177 | View Product |
| ORF Vector | Template DNA | PC638177 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |