RAC1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use RAC1-specific vectors and viral particles designed for reliable RAC1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including RAC1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human RAC1 Gene Overview
| Gene Name | Rac family small GTPase 1 |
|---|---|
| Gene Symbol | RAC1 |
| Synonyms | MIG5,MRD48,Rac-1,TC-25,p21-Rac1 |
| NCBI ID | 5879 |
| Ensembl ID | ENSG00000136238 |
| Uniprot ID | P63000 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Human RAC1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC138393 | View Product |
| AAV Vector & Virus | Long-term expression | VC138393 | View Product |
| Adenovirus | Transient expression | A238393 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG138393 | View Product |
| Gene knockout (non-viral) | PG138393 | View Product | |
| Gene knockout (AAV) | VG138393 | View Product | |
| CRISPR Activation | Gene activation | LA138393 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS138393 | View Product |
| Gene knockdown (AAV) | VS138393 | View Product | |
| ORF Vector | Template DNA | PC138393 | View Product |
Mouse Rac1 Gene Overview
| Gene Name | Rac family small GTPase 1 |
|---|---|
| Gene Symbol | Rac1 |
| Synonyms | D5Ertd559e |
| NCBI ID | 19353 |
| Ensembl ID | ENSMUSG00000001847 |
| Uniprot ID | P63001 |
| Gene Type | Protein coding |
Gene Summary
Enables G protein activity; GTP binding activity; and GTP-dependent protein binding activity. Involved in several processes, including nervous system development; positive regulation of protein localization; and regulation of cell migration. Acts upstream of or within several processes, including actin filament polymerization; generation of neurons; and regulation of intracellular signal transduction. Located in several cellular components, including kinocilium; pericentriolar material; and ruffle membrane. Is active in glutamatergic synapse; synaptic membrane; and synaptic vesicle membrane. Is expressed in several structures, including early conceptus; eye; genitourinary system; nervous system; and organ of Corti. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 48; colorectal cancer (multiple); lung cancer; and pancreatic adenocarcinoma. Orthologous to human RAC1 (Rac family small GTPase 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Rac1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC438393 | View Product |
| AAV Vector & Virus | Long-term expression | VC438393 | View Product |
| Adenovirus | Transient expression | A438393 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG438393 | View Product |
| Gene knockout (non-viral) | PG438393 | View Product | |
| Gene knockout (AAV) | VG438393 | View Product | |
| CRISPR Activation | Gene activation | LA438393 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS438393 | View Product |
| Gene knockdown (AAV) | VS438393 | View Product | |
| ORF Vector | Template DNA | PC438393 | View Product |
Rat Rac1 Gene Overview
| Gene Name | Rac family small GTPase 1 |
|---|---|
| Gene Symbol | Rac1 |
| Synonyms | |
| NCBI ID | 363875 |
| Ensembl ID | ENSRNOG00000001068 |
| Uniprot ID | Q6RUV5 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including GTP binding activity; Rho GDP-dissociation inhibitor binding activity; and enzyme binding activity. Involved in several processes, including actin cytoskeleton organization; bone resorption; and positive regulation of plasma membrane bounded cell projection assembly. Located in Golgi membrane and cytosol. Is active in GABA-ergic synapse. Used to study congestive heart failure. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 48; colorectal cancer (multiple); lung cancer; and pancreatic adenocarcinoma. Orthologous to human RAC1 (Rac family small GTPase 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Rac1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC638393 | View Product |
| AAV Vector & Virus | Long-term expression | VC638393 | View Product |
| Adenovirus | Transient expression | A638393 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG638393 | View Product |
| Gene knockout (non-viral) | PG638393 | View Product | |
| Gene knockout (AAV) | VG638393 | View Product | |
| CRISPR Activation | Gene activation | LA638393 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS638393 | View Product |
| Gene knockdown (AAV) | VS638393 | View Product | |
| ORF Vector | Template DNA | PC638393 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |