RIPK3 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use RIPK3-specific vectors and viral particles designed for reliable RIPK3 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including RIPK3 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human RIPK3 Gene Overview
| Gene Name | receptor interacting serine/threonine kinase 3 |
|---|---|
| Gene Symbol | RIPK3 |
| Synonyms | RIP3 |
| NCBI ID | 11035 |
| Ensembl ID | ENSG00000129465 |
| Uniprot ID | Q9Y572 |
| Gene Type | Protein coding |
Gene Summary
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008]
Human RIPK3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC139612 | View Product |
| AAV Vector & Virus | Long-term expression | VC139612 | View Product |
| Adenovirus | Transient expression | A139612 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG139612 | View Product |
| Gene knockout (non-viral) | PG139612 | View Product | |
| Gene knockout (AAV) | VG139612 | View Product | |
| CRISPR Activation | Gene activation | LA139612 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS139612 | View Product |
| Gene knockdown (AAV) | VS139612 | View Product | |
| ORF Vector | Template DNA | PC139612 | View Product |
Mouse Ripk3 Gene Overview
| Gene Name | receptor-interacting serine-threonine kinase 3 |
|---|---|
| Gene Symbol | Ripk3 |
| Synonyms | Rip3,2610528K09Rik |
| NCBI ID | 56532 |
| Ensembl ID | ENSMUSG00000022221 |
| Uniprot ID | Q9QZL0 |
| Gene Type | Protein coding |
Gene Summary
Enables protein serine/threonine kinase activity. Involved in several processes, including execution phase of necroptosis; hematopoietic or lymphoid organ development; and positive regulation of necroptotic process. Acts upstream of or within with a positive effect on non-canonical NF-kappaB signal transduction. Acts upstream of or within several processes, including positive regulation of intrinsic apoptotic signaling pathway; positive regulation of ligase activity; and regulation of reactive oxygen species metabolic process. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; immune system; male reproductive gland or organ; and turbinate bone primordium. Orthologous to human RIPK3 (receptor interacting serine/threonine kinase 3). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Ripk3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC439612 | View Product |
| Stable overexpression | LC539612 | View Product | |
| AAV Vector & Virus | Long-term expression | VC439612 | View Product |
| Long-term expression | VC539612 | View Product | |
| Adenovirus | Transient expression | A439612 | View Product |
| Transient expression | A539612 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG439612 | View Product |
| Gene knockout (non-viral) | PG439612 | View Product | |
| Gene knockout (AAV) | VG439612 | View Product | |
| CRISPR Activation | Gene activation | LA439612 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS439612 | View Product |
| Gene knockdown (AAV) | VS439612 | View Product | |
| ORF Vector | Template DNA | PC439612 | View Product |
| Template DNA | PC539612 | View Product |
Rat Ripk3 Gene Overview
| Gene Name | receptor-interacting serine-threonine kinase 3 |
|---|---|
| Gene Symbol | Ripk3 |
| Synonyms | Rip3,Hcyp2 |
| NCBI ID | 246240 |
| Ensembl ID | ENSRNOG00000020465 |
| Uniprot ID | Q9Z2P5 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable identical protein binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including hematopoietic or lymphoid organ development; necroptotic process; and regulation of macromolecule metabolic process. Predicted to act upstream of or within with a positive effect on non-canonical NF-kappaB signal transduction. Predicted to act upstream of or within several processes, including positive regulation of intrinsic apoptotic signaling pathway; positive regulation of ligase activity; and positive regulation of reactive oxygen species metabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm. Orthologous to human RIPK3 (receptor interacting serine/threonine kinase 3). [provided by Alliance of Genome Resources, Jul 2025]
Rat Ripk3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC639612 | View Product |
| AAV Vector & Virus | Long-term expression | VC639612 | View Product |
| Adenovirus | Transient expression | A639612 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG639612 | View Product |
| Gene knockout (non-viral) | PG639612 | View Product | |
| Gene knockout (AAV) | VG639612 | View Product | |
| CRISPR Activation | Gene activation | LA639612 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS639612 | View Product |
| Gene knockdown (AAV) | VS639612 | View Product | |
| ORF Vector | Template DNA | PC639612 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |