SLC1A3 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use SLC1A3-specific vectors and viral particles designed for reliable SLC1A3 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including SLC1A3 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human SLC1A3 Gene Overview
| Gene Name | solute carrier family 1 member 3 |
|---|---|
| Gene Symbol | SLC1A3 |
| Synonyms | EA6,EAAT1,GLAST,GLAST1 |
| NCBI ID | 6507 |
| Ensembl ID | ENSG00000079215 |
| Uniprot ID | P43003 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of a member of a high affinity glutamate transporter family. This gene functions in the termination of excitatory neurotransmission in central nervous system. Mutations are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2014]
Human SLC1A3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC143924 | View Product |
| AAV Vector & Virus | Long-term expression | VC143924 | View Product |
| Adenovirus | Transient expression | A143924 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG143924 | View Product |
| Gene knockout (non-viral) | PG143924 | View Product | |
| Gene knockout (AAV) | VG143924 | View Product | |
| CRISPR Activation | Gene activation | LA143924 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS143924 | View Product |
| Gene knockdown (AAV) | VS143924 | View Product | |
| ORF Vector | Template DNA | PC143924 | View Product |
Mouse Slc1a3 Gene Overview
| Gene Name | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
|---|---|
| Gene Symbol | Slc1a3 |
| Synonyms | Gmt1,Eaat1,GLAST,GLU-T,GluT-1,MGluT1,GLAST-1,B430115D02Rik |
| NCBI ID | 20512 |
| Ensembl ID | ENSMUSG00000005360 |
| Uniprot ID | P56564 |
| Gene Type | Protein coding |
Gene Summary
Enables glutamate binding activity and high-affinity L-glutamate transmembrane transporter activity. Involved in D-aspartate import across plasma membrane and cellular response to cocaine. Acts upstream of or within several processes, including L-glutamate import across plasma membrane; gamma-aminobutyric acid biosynthetic process; and nervous system development. Located in several cellular components, including cell surface; neuron projection; and neuronal cell body. Is expressed in several structures, including central nervous system; connective tissue; eye; foregut; and genitourinary system. Used to study low tension glaucoma. Human ortholog(s) of this gene implicated in episodic ataxia type 6. Orthologous to human SLC1A3 (solute carrier family 1 member 3). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Slc1a3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC443924 | View Product |
| AAV Vector & Virus | Long-term expression | VC443924 | View Product |
| Adenovirus | Transient expression | A443924 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG443924 | View Product |
| Gene knockout (non-viral) | PG443924 | View Product | |
| Gene knockout (AAV) | VG443924 | View Product | |
| CRISPR Activation | Gene activation | LA443924 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS443924 | View Product |
| Gene knockdown (AAV) | VS443924 | View Product | |
| ORF Vector | Template DNA | PC443924 | View Product |
Rat Slc1a3 Gene Overview
| Gene Name | solute carrier family 1 member 3 |
|---|---|
| Gene Symbol | Slc1a3 |
| Synonyms | EAAT1,GLAST,GluT-1,GLAST-1 |
| NCBI ID | 29483 |
| Ensembl ID | ENSRNOG00000016163 |
| Uniprot ID | P24942 |
| Gene Type | Protein coding |
Gene Summary
Enables high-affinity L-glutamate transmembrane transporter activity. Involved in L-aspartate import across plasma membrane; L-glutamate import across plasma membrane; and malate-aspartate shuttle. Acts upstream of or within L-glutamate transmembrane transport. Located in several cellular components, including basolateral plasma membrane; dendritic spine; and neuronal cell body. Part of membrane protein complex. Human ortholog(s) of this gene implicated in episodic ataxia type 6. Orthologous to human SLC1A3 (solute carrier family 1 member 3). [provided by Alliance of Genome Resources, Jul 2025]
Rat Slc1a3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC643924 | View Product |
| AAV Vector & Virus | Long-term expression | VC643924 | View Product |
| Adenovirus | Transient expression | A643924 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG643924 | View Product |
| Gene knockout (non-viral) | PG643924 | View Product | |
| Gene knockout (AAV) | VG643924 | View Product | |
| CRISPR Activation | Gene activation | LA643924 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS643924 | View Product |
| Gene knockdown (AAV) | VS643924 | View Product | |
| ORF Vector | Template DNA | PC643924 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |