SLC7A11 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use SLC7A11-specific vectors and viral particles designed for reliable SLC7A11 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including SLC7A11 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human SLC7A11 Gene Overview
| Gene Name | solute carrier family 7 member 11 |
|---|---|
| Gene Symbol | SLC7A11 |
| Synonyms | xCT,CCBR1 |
| NCBI ID | 23657 |
| Ensembl ID | ENSG00000151012 |
| Uniprot ID | Q9UPY5 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
Human SLC7A11 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC144272 | View Product |
| AAV Vector & Virus | Long-term expression | VC144272 | View Product |
| Adenovirus | Transient expression | A144272 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG144272 | View Product |
| Gene knockout (non-viral) | PG144272 | View Product | |
| Gene knockout (AAV) | VG144272 | View Product | |
| CRISPR Activation | Gene activation | LA144272 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS144272 | View Product |
| Gene knockdown (AAV) | VS144272 | View Product | |
| ORF Vector | Template DNA | PC144272 | View Product |
Mouse Slc7a11 Gene Overview
| Gene Name | solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 |
|---|---|
| Gene Symbol | Slc7a11 |
| Synonyms | sut,xCT,9930009M05Rik |
| NCBI ID | 26570 |
| Ensembl ID | ENSMUSG00000027737 |
| Uniprot ID | Q9WTR6 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable L-kynurenine transmembrane transporter activity and cystine:glutamate antiporter activity. Involved in L-cystine transport. Acts upstream of or within several processes, including oligopeptide transmembrane transport; regulation of amino acid metabolic process; and regulation of protein localization. Located in apical part of cell; astrocyte projection; and brush border membrane. Is expressed in brain; eye; olfactory epithelium; and spinal cord meninges. Used to study Hermansky-Pudlak syndrome and platelet storage pool deficiency. Orthologous to human SLC7A11 (solute carrier family 7 member 11). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Slc7a11 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC444272 | View Product |
| AAV Vector & Virus | Long-term expression | VC444272 | View Product |
| Adenovirus | Transient expression | A444272 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG444272 | View Product |
| Gene knockout (non-viral) | PG444272 | View Product | |
| Gene knockout (AAV) | VG444272 | View Product | |
| CRISPR Activation | Gene activation | LA444272 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS444272 | View Product |
| Gene knockdown (AAV) | VS444272 | View Product | |
| ORF Vector | Template DNA | PC444272 | View Product |
Rat Slc7a11 Gene Overview
| Gene Name | solute carrier family 7 member 11 |
|---|---|
| Gene Symbol | Slc7a11 |
| Synonyms | |
| NCBI ID | 310392 |
| Ensembl ID | ENSRNOG00000010210 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable L-kynurenine transmembrane transporter activity and cystine:glutamate antiporter activity. Involved in lens fiber cell differentiation; response to nicotine; and response to oxidative stress. Predicted to be located in several cellular components, including astrocyte projection; brush border membrane; and cell surface. Orthologous to human SLC7A11 (solute carrier family 7 member 11). [provided by Alliance of Genome Resources, Apr 2025]
Rat Slc7a11 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC644272 | View Product |
| AAV Vector & Virus | Long-term expression | VC644272 | View Product |
| Adenovirus | Transient expression | A644272 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG644272 | View Product |
| Gene knockout (non-viral) | PG644272 | View Product | |
| Gene knockout (AAV) | VG644272 | View Product | |
| CRISPR Activation | Gene activation | LA644272 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS644272 | View Product |
| Gene knockdown (AAV) | VS644272 | View Product | |
| ORF Vector | Template DNA | PC644272 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |