SMPDL3B Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use SMPDL3B-specific vectors and viral particles designed for reliable SMPDL3B overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including SMPDL3B CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human SMPDL3B Gene Overview
| Gene Name | sphingomyelin phosphodiesterase acid like 3B |
|---|---|
| Gene Symbol | SMPDL3B |
| Synonyms | ASML3B |
| NCBI ID | 27293 |
| Ensembl ID | ENSG00000130768 |
| Uniprot ID | Q92485 |
| Gene Type | Protein coding |
Gene Summary
Enables phosphoric diester hydrolase activity. Predicted to be involved in membrane lipid catabolic process; negative regulation of inflammatory response; and negative regulation of toll-like receptor signaling pathway. Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]
Human SMPDL3B Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC144473 | View Product |
| AAV Vector & Virus | Long-term expression | VC144473 | View Product |
| Adenovirus | Transient expression | A144473 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG144473 | View Product |
| Gene knockout (non-viral) | PG144473 | View Product | |
| Gene knockout (AAV) | VG144473 | View Product | |
| CRISPR Activation | Gene activation | LA144473 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS144473 | View Product |
| Gene knockdown (AAV) | VS144473 | View Product | |
| ORF Vector | Template DNA | PC144473 | View Product |
Mouse Smpdl3b Gene Overview
| Gene Name | sphingomyelin phosphodiesterase, acid-like 3B |
|---|---|
| Gene Symbol | Smpdl3b |
| Synonyms | Asml3b,1110054A24Rik |
| NCBI ID | 100340 |
| Ensembl ID | ENSMUSG00000028885 |
| Uniprot ID | P58242 |
| Gene Type | Protein coding |
Gene Summary
Enables phosphoric diester hydrolase activity and zinc ion binding activity. Involved in membrane lipid catabolic process; negative regulation of inflammatory response; and negative regulation of toll-like receptor signaling pathway. Located in plasma membrane. Orthologous to human SMPDL3B (sphingomyelin phosphodiesterase acid like 3B). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Smpdl3b Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC444473 | View Product |
| AAV Vector & Virus | Long-term expression | VC444473 | View Product |
| Adenovirus | Transient expression | A444473 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG444473 | View Product |
| Gene knockout (non-viral) | PG444473 | View Product | |
| Gene knockout (AAV) | VG444473 | View Product | |
| CRISPR Activation | Gene activation | LA444473 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS444473 | View Product |
| Gene knockdown (AAV) | VS444473 | View Product | |
| ORF Vector | Template DNA | PC444473 | View Product |
Rat Smpdl3b Gene Overview
| Gene Name | sphingomyelin phosphodiesterase, acid-like 3B |
|---|---|
| Gene Symbol | Smpdl3b |
| Synonyms | |
| NCBI ID | 362619 |
| Ensembl ID | ENSRNOG00000042326 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable phosphoric diester hydrolase activity and zinc ion binding activity. Predicted to be involved in membrane lipid catabolic process; negative regulation of inflammatory response; and negative regulation of toll-like receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Orthologous to human SMPDL3B (sphingomyelin phosphodiesterase acid like 3B). [provided by Alliance of Genome Resources, Jul 2025]
Rat Smpdl3b Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC644473 | View Product |
| AAV Vector & Virus | Long-term expression | VC644473 | View Product |
| Adenovirus | Transient expression | A644473 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG644473 | View Product |
| Gene knockout (non-viral) | PG644473 | View Product | |
| Gene knockout (AAV) | VG644473 | View Product | |
| CRISPR Activation | Gene activation | LA644473 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS644473 | View Product |
| Gene knockdown (AAV) | VS644473 | View Product | |
| ORF Vector | Template DNA | PC644473 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |