SOX1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use SOX1-specific vectors and viral particles designed for reliable SOX1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including SOX1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human SOX1 Gene Overview
| Gene Name | SRY-box transcription factor 1 |
|---|---|
| Gene Symbol | SOX1 |
| Synonyms | |
| NCBI ID | 6656 |
| Ensembl ID | ENSG00000182968 |
| Uniprot ID | O00570 |
| Gene Type | Protein coding |
Gene Summary
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq, Jul 2008]
Human SOX1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC145132 | View Product |
| AAV Vector & Virus | Long-term expression | VC145132 | View Product |
| Adenovirus | Transient expression | A145132 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG145132 | View Product |
| Gene knockout (non-viral) | PG145132 | View Product | |
| Gene knockout (AAV) | VG145132 | View Product | |
| CRISPR Activation | Gene activation | LA145132 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS145132 | View Product |
| Gene knockdown (AAV) | VS145132 | View Product | |
| ORF Vector | Template DNA | PC145132 | View Product |
Mouse Sox1 Gene Overview
| Gene Name | SRY (sex determining region Y)-box 1 |
|---|---|
| Gene Symbol | Sox1 |
| Synonyms | Sox-1 |
| NCBI ID | 20664 |
| Ensembl ID | ENSMUSG00000096014 |
| Uniprot ID | P53783 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in interneuron migration; regulation of oligodendrocyte differentiation; and regulation of transcription by RNA polymerase II. Acts upstream of or within cellular response to leukemia inhibitory factor; generation of neurons; and lens morphogenesis in camera-type eye. Located in nucleus. Is expressed in several structures, including central nervous system; eye; genitourinary system; large intestine; and neural ectoderm. Orthologous to human SOX1 (SRY-box transcription factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Sox1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC445132 | View Product |
| AAV Vector & Virus | Long-term expression | VC445132 | View Product |
| Adenovirus | Transient expression | A445132 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG445132 | View Product |
| Gene knockout (non-viral) | PG445132 | View Product | |
| Gene knockout (AAV) | VG445132 | View Product | |
| CRISPR Activation | Gene activation | LA445132 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS445132 | View Product |
| Gene knockdown (AAV) | VS445132 | View Product | |
| ORF Vector | Template DNA | PC445132 | View Product |
Rat Sox1 Gene Overview
| Gene Name | SRY-box transcription factor 1 |
|---|---|
| Gene Symbol | Sox1 |
| Synonyms | |
| NCBI ID | 100912302 |
| Ensembl ID | ENSRNOG00000064976 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in nervous system development; regulation of oligodendrocyte differentiation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular response to leukemia inhibitory factor; generation of neurons; and lens morphogenesis in camera-type eye. Predicted to be active in nucleus. Orthologous to human SOX1 (SRY-box transcription factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Sox1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |