SOX10 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use SOX10-specific vectors and viral particles designed for reliable SOX10 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including SOX10 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human SOX10 Gene Overview
| Gene Name | SRY-box transcription factor 10 |
|---|---|
| Gene Symbol | SOX10 |
| Synonyms | DOM,WS4,PCWH,WS2E,WS4C,SOX-10 |
| NCBI ID | 6663 |
| Ensembl ID | ENSG00000100146 |
| Uniprot ID | P56693 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq, Jul 2008]
Human SOX10 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC145133 | View Product |
| AAV Vector & Virus | Long-term expression | VC145133 | View Product |
| Adenovirus | Transient expression | A145133 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG145133 | View Product |
| Gene knockout (non-viral) | PG145133 | View Product | |
| Gene knockout (AAV) | VG145133 | View Product | |
| CRISPR Activation | Gene activation | LA145133 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS145133 | View Product |
| Gene knockdown (AAV) | VS145133 | View Product | |
| ORF Vector | Template DNA | PC145133 | View Product |
Mouse Sox10 Gene Overview
| Gene Name | SRY (sex determining region Y)-box 10 |
|---|---|
| Gene Symbol | Sox10 |
| Synonyms | gt,Dom,Sox21 |
| NCBI ID | 20665 |
| Ensembl ID | ENSMUSG00000033006 |
| Uniprot ID | Q04888 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including negative regulation of canonical Wnt signaling pathway; nervous system development; and neural crest cell migration. Acts upstream of or within several processes, including lacrimal gland development; melanocyte differentiation; and positive regulation of neuroblast proliferation. Located in mitochondrial outer membrane and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; inner ear; mesenchyme derived from neural crest; and nervous system. Used to study Kallmann syndrome; PCWH syndrome; and Waardenburg syndrome type 4C. Human ortholog(s) of this gene implicated in Kallmann syndrome; PCWH syndrome; Waardenburg syndrome type 2E; and Waardenburg syndrome type 4C. Orthologous to human SOX10 (SRY-box transcription factor 10). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Sox10 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC445133 | View Product |
| AAV Vector & Virus | Long-term expression | VC445133 | View Product |
| Adenovirus | Transient expression | A445133 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG445133 | View Product |
| Gene knockout (non-viral) | PG445133 | View Product | |
| Gene knockout (AAV) | VG445133 | View Product | |
| CRISPR Activation | Gene activation | LA445133 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS445133 | View Product |
| Gene knockdown (AAV) | VS445133 | View Product | |
| ORF Vector | Template DNA | PC445133 | View Product |
Rat Sox10 Gene Overview
| Gene Name | SRY-box transcription factor 10 |
|---|---|
| Gene Symbol | Sox10 |
| Synonyms | |
| NCBI ID | 29361 |
| Ensembl ID | ENSRNOG00000011305 |
| Uniprot ID | O55170 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including DNA-binding transcription activator activity; promoter-specific chromatin binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to progesterone stimulus; regulation of gene expression; and regulation of nervous system development. Located in chromatin. Human ortholog(s) of this gene implicated in Kallmann syndrome; PCWH syndrome; Waardenburg syndrome type 2E; and Waardenburg syndrome type 4C. Orthologous to human SOX10 (SRY-box transcription factor 10). [provided by Alliance of Genome Resources, Jul 2025]
Rat Sox10 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC645133 | View Product |
| AAV Vector & Virus | Long-term expression | VC645133 | View Product |
| Adenovirus | Transient expression | A645133 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG645133 | View Product |
| Gene knockout (non-viral) | PG645133 | View Product | |
| Gene knockout (AAV) | VG645133 | View Product | |
| CRISPR Activation | Gene activation | LA645133 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS645133 | View Product |
| Gene knockdown (AAV) | VS645133 | View Product | |
| ORF Vector | Template DNA | PC645133 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |