STAT2 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use STAT2-specific vectors and viral particles designed for reliable STAT2 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including STAT2 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human STAT2 Gene Overview
| Gene Name | signal transducer and activator of transcription 2 |
|---|---|
| Gene Symbol | STAT2 |
| Synonyms | P113,IMD44,ISGF-3,PTORCH3,STAT113 |
| NCBI ID | 6773 |
| Ensembl ID | ENSG00000170581 |
| Uniprot ID | P52630 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. The protein mediates innate antiviral activity. Mutations in this gene result in Immunodeficiency 44. [provided by RefSeq, Aug 2020]
Human STAT2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC145696 | View Product |
| AAV Vector & Virus | Long-term expression | VC145696 | View Product |
| Adenovirus | Transient expression | A245696 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG145696 | View Product |
| Gene knockout (non-viral) | PG145696 | View Product | |
| Gene knockout (AAV) | VG145696 | View Product | |
| CRISPR Activation | Gene activation | LA145696 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS145696 | View Product |
| Gene knockdown (AAV) | VS145696 | View Product | |
| ORF Vector | Template DNA | PC145696 | View Product |
Mouse Stat2 Gene Overview
| Gene Name | signal transducer and activator of transcription 2 |
|---|---|
| Gene Symbol | Stat2 |
| Synonyms | 1600010G07Rik |
| NCBI ID | 20847 |
| Ensembl ID | ENSMUSG00000040033 |
| Uniprot ID | Q9WVL2 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; identical protein binding activity; and ubiquitin-like protein ligase binding activity. Involved in negative regulation of type I interferon-mediated signaling pathway and type I interferon-mediated signaling pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; and genitourinary system. Used to study Zika fever. Human ortholog(s) of this gene implicated in Zika fever; immunodeficiency 44; and neutropenia. Orthologous to human STAT2 (signal transducer and activator of transcription 2). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Stat2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC445696 | View Product |
| AAV Vector & Virus | Long-term expression | VC445696 | View Product |
| Adenovirus | Transient expression | A445696 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG445696 | View Product |
| Gene knockout (non-viral) | PG445696 | View Product | |
| Gene knockout (AAV) | VG445696 | View Product | |
| CRISPR Activation | Gene activation | LA445696 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS445696 | View Product |
| Gene knockdown (AAV) | VS445696 | View Product | |
| ORF Vector | Template DNA | PC445696 | View Product |
Rat Stat2 Gene Overview
| Gene Name | signal transducer and activator of transcription 2 |
|---|---|
| Gene Symbol | Stat2 |
| Synonyms | |
| NCBI ID | 288774 |
| Ensembl ID | ENSRNOG00000031081 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; identical protein binding activity; and ubiquitin-like protein ligase binding activity. Predicted to be involved in several processes, including defense response to other organism; negative regulation of type I interferon-mediated signaling pathway; and regulation of primary metabolic process. Predicted to be located in cytosol and plasma membrane. Predicted to be part of ISGF3 complex. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Zika fever; immunodeficiency 44; and neutropenia. Orthologous to human STAT2 (signal transducer and activator of transcription 2). [provided by Alliance of Genome Resources, Apr 2025]
Rat Stat2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC645696 | View Product |
| AAV Vector & Virus | Long-term expression | VC645696 | View Product |
| Adenovirus | Transient expression | A645696 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG645696 | View Product |
| Gene knockout (non-viral) | PG645696 | View Product | |
| Gene knockout (AAV) | VG645696 | View Product | |
| CRISPR Activation | Gene activation | LA645696 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS645696 | View Product |
| Gene knockdown (AAV) | VS645696 | View Product | |
| ORF Vector | Template DNA | PC645696 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |