STEAP4 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use STEAP4-specific vectors and viral particles designed for reliable STEAP4 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including STEAP4 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human STEAP4 Gene Overview
| Gene Name | STEAP4 metalloreductase |
|---|---|
| Gene Symbol | STEAP4 |
| Synonyms | TIARP,STAMP2,SchLAH,TNFAIP9 |
| NCBI ID | 79689 |
| Ensembl ID | ENSG00000127954 |
| Uniprot ID | Q687X5 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]
Human STEAP4 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC145715 | View Product |
| AAV Vector & Virus | Long-term expression | VC145715 | View Product |
| Adenovirus | Transient expression | A145715 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG145715 | View Product |
| Gene knockout (non-viral) | PG145715 | View Product | |
| Gene knockout (AAV) | VG145715 | View Product | |
| CRISPR Activation | Gene activation | LA145715 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS145715 | View Product |
| Gene knockdown (AAV) | VS145715 | View Product | |
| ORF Vector | Template DNA | PC145715 | View Product |
Mouse Steap4 Gene Overview
| Gene Name | STEAP family member 4 |
|---|---|
| Gene Symbol | Steap4 |
| Synonyms | Tiarp,Tnfaip9,1110021O17Rik |
| NCBI ID | 117167 |
| Ensembl ID | ENSMUSG00000012428 |
| Uniprot ID | Q923B6 |
| Gene Type | Protein coding |
Gene Summary
Enables cupric reductase (NADH) activity and ferric-chelate reductase (NADPH) activity. Involved in fat cell differentiation. Acts upstream of or within copper ion import; iron import into cell; and iron ion import across cell outer membrane. Located in endosome and plasma membrane. Is expressed in brain. Orthologous to human STEAP4 (STEAP4 metalloreductase). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Steap4 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC445715 | View Product |
| AAV Vector & Virus | Long-term expression | VC445715 | View Product |
| Adenovirus | Transient expression | A445715 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG445715 | View Product |
| Gene knockout (non-viral) | PG445715 | View Product | |
| Gene knockout (AAV) | VG445715 | View Product | |
| CRISPR Activation | Gene activation | LA445715 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS445715 | View Product |
| Gene knockdown (AAV) | VS445715 | View Product | |
| ORF Vector | Template DNA | PC445715 | View Product |
Rat Steap4 Gene Overview
| Gene Name | STEAP4 metalloreductase |
|---|---|
| Gene Symbol | Steap4 |
| Synonyms | |
| NCBI ID | 499991 |
| Ensembl ID | ENSRNOG00000008602 |
| Uniprot ID | Q4V8K1 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including FAD binding activity; heme binding activity; and oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor. Predicted to be involved in copper ion import; fat cell differentiation; and protein homotrimerization. Predicted to act upstream of or within iron import into cell. Predicted to be located in membrane and nucleoplasm. Predicted to be active in endosome and plasma membrane. Orthologous to human STEAP4 (STEAP4 metalloreductase). [provided by Alliance of Genome Resources, Jul 2025]
Rat Steap4 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC645715 | View Product |
| AAV Vector & Virus | Long-term expression | VC645715 | View Product |
| Adenovirus | Transient expression | A645715 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG645715 | View Product |
| Gene knockout (non-viral) | PG645715 | View Product | |
| Gene knockout (AAV) | VG645715 | View Product | |
| CRISPR Activation | Gene activation | LA645715 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS645715 | View Product |
| Gene knockdown (AAV) | VS645715 | View Product | |
| ORF Vector | Template DNA | PC645715 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |