TET1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use TET1-specific vectors and viral particles designed for reliable TET1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including TET1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human TET1 Gene Overview
| Gene Name | tet methylcytosine dioxygenase 1 |
|---|---|
| Gene Symbol | TET1 |
| Synonyms | LCX,CXXC6,bA119F7.1 |
| NCBI ID | 80312 |
| Ensembl ID | ENSG00000138336 |
| Uniprot ID | Q8NFU7 |
| Gene Type | Protein coding |
Gene Summary
DNA methylation is an epigenetic mechanism that is important for controlling gene expression. The protein encoded by this gene is a demethylase that belongs to the TET (ten-eleven translocation) family. Members of the TET protein family play a role in the DNA methylation process and gene activation. [provided by RefSeq, Sep 2015]
Human TET1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| CRISPR KO Tools | Gene knockout (non-viral) | PG146518 | View Product |
| Gene knockout (AAV) | VG146518 | View Product | |
| CRISPR Activation | Gene activation | LA146518 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS146518 | View Product |
| Gene knockdown (AAV) | VS146518 | View Product | |
| ORF Vector | Template DNA | PC146518 | View Product |
Mouse Tet1 Gene Overview
| Gene Name | tet methylcytosine dioxygenase 1 |
|---|---|
| Gene Symbol | Tet1 |
| Synonyms | LCX,Cxxc6,mKIAA1676,D10Ertd17e,2510010B09Rik |
| NCBI ID | 52463 |
| Ensembl ID | ENSMUSG00000047146 |
| Uniprot ID | Q3URK3 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA 5-methylcytosine dioxygenase activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including dendrite morphogenesis; inner cell mass cell differentiation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within epigenetic programing of male pronucleus and positive regulation of gene expression via chromosomal CpG island demethylation. Located in nucleus. Is expressed in several structures, including brain; early conceptus; immune system; lower urogenital tract; and reproductive system. Orthologous to human TET1 (tet methylcytosine dioxygenase 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Tet1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG446518 | View Product |
| Gene knockout (non-viral) | PG446518 | View Product | |
| Gene knockout (AAV) | VG446518 | View Product | |
| CRISPR Activation | Gene activation | LA446518 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS446518 | View Product |
| Gene knockdown (AAV) | VS446518 | View Product | |
| ORF Vector | Template DNA | PC446518 | View Product |
Rat Tet1 Gene Overview
| Gene Name | tet methylcytosine dioxygenase 1 |
|---|---|
| Gene Symbol | Tet1 |
| Synonyms | Cxxc6 |
| NCBI ID | 309902 |
| Ensembl ID | ENSRNOG00000000277 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable DNA 5-methylcytosine dioxygenase activity; sequence-specific DNA binding activity; and transition metal ion binding activity. Predicted to be involved in several processes, including cellular response to reactive oxygen species; dendrite morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within epigenetic programing of male pronucleus; inner cell mass cell differentiation; and positive regulation of gene expression via chromosomal CpG island demethylation. Predicted to be located in chromosome. Predicted to be active in nucleus. Orthologous to human TET1 (tet methylcytosine dioxygenase 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Tet1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG646518 | View Product |
| Gene knockout (non-viral) | PG646518 | View Product | |
| Gene knockout (AAV) | VG646518 | View Product | |
| CRISPR Activation | Gene activation | LA646518 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS646518 | View Product |
| Gene knockdown (AAV) | VS646518 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |