TET2 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use TET2-specific vectors and viral particles designed for reliable TET2 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including TET2 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human TET2 Gene Overview
| Gene Name | tet methylcytosine dioxygenase 2 |
|---|---|
| Gene Symbol | TET2 |
| Synonyms | MDS,IMD75,KIAA1546 |
| NCBI ID | 54790 |
| Ensembl ID | ENSG00000168769 |
| Uniprot ID | Q6N021 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Human TET2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC146520 | View Product |
| AAV Vector & Virus | Long-term expression | VC146520 | View Product |
| Adenovirus | Transient expression | A146520 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG146520 | View Product |
| Gene knockout (non-viral) | PG146520 | View Product | |
| Gene knockout (AAV) | VG146520 | View Product | |
| CRISPR Activation | Gene activation | LA146520 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS146520 | View Product |
| Gene knockdown (AAV) | VS146520 | View Product | |
| ORF Vector | Template DNA | PC146520 | View Product |
Mouse Tet2 Gene Overview
| Gene Name | tet methylcytosine dioxygenase 2 |
|---|---|
| Gene Symbol | Tet2 |
| Synonyms | Ayu17-449,mKIAA1546,E130014J05Rik |
| NCBI ID | 214133 |
| Ensembl ID | ENSMUSG00000040943 |
| Uniprot ID | Q4JK59 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA 5-methylcytosine dioxygenase activity. Involved in myeloid cell differentiation; positive regulation of transcription by RNA polymerase II; and protein O-linked glycosylation. Acts upstream of or within several processes, including hematopoietic stem cell homeostasis; myeloid progenitor cell differentiation; and positive regulation of gene expression, epigenetic. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brain; extraembryonic component; immune system; lower urogenital tract; and reproductive system. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); hematologic cancer (multiple); lung non-small cell carcinoma; and primary immunodeficiency disease. Orthologous to human TET2 (tet methylcytosine dioxygenase 2). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Tet2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Adenovirus | Transient expression | A446520 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG446520 | View Product |
| Gene knockout (non-viral) | PG446520 | View Product | |
| Gene knockout (AAV) | VG446520 | View Product | |
| CRISPR Activation | Gene activation | LA446520 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS446520 | View Product |
| Gene knockdown (AAV) | VS446520 | View Product | |
| ORF Vector | Template DNA | PC446520 | View Product |
Rat Tet2 Gene Overview
| Gene Name | tet methylcytosine dioxygenase 2 |
|---|---|
| Gene Symbol | Tet2 |
| Synonyms | RGD1311625 |
| NCBI ID | 310859 |
| Ensembl ID | ENSRNOG00000023579 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable DNA 5-methylcytosine dioxygenase activity; ferrous iron binding activity; and zinc ion binding activity. Predicted to be involved in hemopoiesis; positive regulation of transcription by RNA polymerase II; and protein O-linked glycosylation. Predicted to act upstream of or within several processes, including hematopoietic stem cell homeostasis; myeloid progenitor cell differentiation; and positive regulation of gene expression, epigenetic. Predicted to be located in chromosome. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); hematologic cancer (multiple); lung non-small cell carcinoma; and primary immunodeficiency disease. Orthologous to human TET2 (tet methylcytosine dioxygenase 2). [provided by Alliance of Genome Resources, Jul 2025]
Rat Tet2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |