TFRC Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use TFRC-specific vectors and viral particles designed for reliable TFRC overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including TFRC CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human TFRC Gene Overview
| Gene Name | transferrin receptor |
|---|---|
| Gene Symbol | TFRC |
| Synonyms | T9,TR,TFR,p90,CD71,TFR1,TRFR,IMD46 |
| NCBI ID | 7037 |
| Ensembl ID | ENSG00000072274 |
| Uniprot ID | P02786 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
Human TFRC Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC146583 | View Product |
| AAV Vector & Virus | Long-term expression | VC146583 | View Product |
| Adenovirus | Transient expression | A146583 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG146583 | View Product |
| Gene knockout (non-viral) | PG146583 | View Product | |
| Gene knockout (AAV) | VG146583 | View Product | |
| CRISPR Activation | Gene activation | LA146583 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS146583 | View Product |
| Gene knockdown (AAV) | VS146583 | View Product | |
| ORF Vector | Template DNA | PC146583 | View Product |
Mouse Tfrc Gene Overview
| Gene Name | transferrin receptor |
|---|---|
| Gene Symbol | Tfrc |
| Synonyms | TR,TFR,p90,CD71,TFR1,Trfr,Mtvr1,2610028K12Rik,E430033M20Rik |
| NCBI ID | 22042 |
| Ensembl ID | ENSMUSG00000022797 |
| Uniprot ID | Q62351 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis. [provided by RefSeq, Sep 2015]
Mouse Tfrc Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC446583 | View Product |
| AAV Vector & Virus | Long-term expression | VC446583 | View Product |
| Adenovirus | Transient expression | A446583 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG446583 | View Product |
| Gene knockout (non-viral) | PG446583 | View Product | |
| Gene knockout (AAV) | VG446583 | View Product | |
| CRISPR Activation | Gene activation | LA446583 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS446583 | View Product |
| Gene knockdown (AAV) | VS446583 | View Product | |
| ORF Vector | Template DNA | PC446583 | View Product |
Rat Tfrc Gene Overview
| Gene Name | transferrin receptor |
|---|---|
| Gene Symbol | Tfrc |
| Synonyms | Trfr |
| NCBI ID | 64678 |
| Ensembl ID | ENSRNOG00000001766 |
| Uniprot ID | Q99376 |
| Gene Type | Protein coding |
Gene Summary
Enables Hsp70 protein binding activity and transferrin receptor activity. Involved in several processes, including response to copper ion; response to manganese ion; and response to retinoic acid. Located in several cellular components, including cell surface; extracellular space; and recycling endosome membrane. Is active in glutamatergic synapse and postsynaptic recycling endosome membrane. Biomarker of duodenal ulcer; hepatocellular carcinoma; metabolic dysfunction-associated steatotic liver disease; muscular atrophy; and nutrition disease. Human ortholog(s) of this gene implicated in breast carcinoma; immunodeficiency 46; multiple myeloma; and ovarian cancer. Orthologous to human TFRC (transferrin receptor). [provided by Alliance of Genome Resources, Jul 2025]
Rat Tfrc Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC646583 | View Product |
| AAV Vector & Virus | Long-term expression | VC646583 | View Product |
| Adenovirus | Transient expression | A646583 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG646583 | View Product |
| Gene knockout (non-viral) | PG646583 | View Product | |
| Gene knockout (AAV) | VG646583 | View Product | |
| CRISPR Activation | Gene activation | LA646583 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS646583 | View Product |
| Gene knockdown (AAV) | VS646583 | View Product | |
| ORF Vector | Template DNA | PC646583 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |