THBS1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use THBS1-specific vectors and viral particles designed for reliable THBS1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including THBS1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human THBS1 Gene Overview
| Gene Name | thrombospondin 1 |
|---|---|
| Gene Symbol | THBS1 |
| Synonyms | TSP,THBS,TSP1,TSP-1,THBS-1 |
| NCBI ID | 7057 |
| Ensembl ID | ENSG00000137801 |
| Uniprot ID | P07996 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]
Human THBS1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC146641 | View Product |
| Adenovirus | Transient expression | A146641 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG146641 | View Product |
| Gene knockout (non-viral) | PG146641 | View Product | |
| Gene knockout (AAV) | VG146641 | View Product | |
| CRISPR Activation | Gene activation | LA146641 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS146641 | View Product |
| Gene knockdown (AAV) | VS146641 | View Product | |
| ORF Vector | Template DNA | PC146641 | View Product |
Mouse Thbs1 Gene Overview
| Gene Name | thrombospondin 1 |
|---|---|
| Gene Symbol | Thbs1 |
| Synonyms | TSP1,TSP-1,tbsp1,Thbs-1 |
| NCBI ID | 21825 |
| Ensembl ID | ENSMUSG00000040152 |
| Uniprot ID | P35441 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
Mouse Thbs1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC446641 | View Product |
| Adenovirus | Transient expression | A446641 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG446641 | View Product |
| Gene knockout (non-viral) | PG446641 | View Product | |
| Gene knockout (AAV) | VG446641 | View Product | |
| CRISPR Activation | Gene activation | LA446641 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS446641 | View Product |
| Gene knockdown (AAV) | VS446641 | View Product | |
| ORF Vector | Template DNA | PC446641 | View Product |
Rat Thbs1 Gene Overview
| Gene Name | thrombospondin 1 |
|---|---|
| Gene Symbol | Thbs1 |
| Synonyms | Tsp1,TSP-1 |
| NCBI ID | 445442 |
| Ensembl ID | ENSRNOG00000045829 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Enables transforming growth factor beta binding activity. Involved in several processes, including cellular response to tumor necrosis factor; positive regulation of transforming growth factor beta production; and response to testosterone. Located in extracellular space. Biomarker of diabetic retinopathy; heart disease; myocardial infarction; and prostate cancer. Human ortholog(s) of this gene implicated in cholangiocarcinoma; pancreatic cancer; pancreatic ductal carcinoma; and primary open angle glaucoma. Orthologous to human THBS1 (thrombospondin 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Thbs1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC646641 | View Product |
| Adenovirus | Transient expression | A646641 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG646641 | View Product |
| Gene knockout (non-viral) | PG646641 | View Product | |
| Gene knockout (AAV) | VG646641 | View Product | |
| CRISPR Activation | Gene activation | LA646641 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS646641 | View Product |
| Gene knockdown (AAV) | VS646641 | View Product | |
| ORF Vector | Template DNA | PC646641 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |