TNNC1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use TNNC1-specific vectors and viral particles designed for reliable TNNC1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including TNNC1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human TNNC1 Gene Overview
| Gene Name | troponin C1, slow skeletal and cardiac type |
|---|---|
| Gene Symbol | TNNC1 |
| Synonyms | TNC,TN-C,TNNC,CMD1Z,CMH13 |
| NCBI ID | 7134 |
| Ensembl ID | ENSG00000114854 |
| Uniprot ID | P63316 |
| Gene Type | Protein coding |
Gene Summary
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]
Human TNNC1 Related Products
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Mouse Tnnc1 Gene Overview
| Gene Name | troponin C, cardiac/slow skeletal |
|---|---|
| Gene Symbol | Tnnc1 |
| Synonyms | TnC,cTnC,cTnI,tncc |
| NCBI ID | 21924 |
| Ensembl ID | ENSMUSG00000091898 |
| Uniprot ID | P19123 |
| Gene Type | Protein coding |
Gene Summary
Enables actin filament binding activity. Involved in regulation of ATP-dependent activity and regulation of muscle filament sliding speed. Acts upstream of or within transition between fast and slow fiber. Part of cardiac Troponin complex. Is expressed in several structures, including alimentary system; heart; liver; metanephros; and skeletal muscle. Used to study hypertrophic cardiomyopathy 13. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1Z; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 13. Orthologous to human TNNC1 (troponin C1, slow skeletal and cardiac type). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Tnnc1 Related Products
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Rat Gene Overview
| Gene Name | |
|---|---|
| Gene Symbol | |
| Synonyms | |
| NCBI ID | 64550 |
| Ensembl ID | |
| Uniprot ID | |
| Gene Type |
Gene Summary
Rat Related Products
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Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |