TRIM21 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use TRIM21-specific vectors and viral particles designed for reliable TRIM21 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including TRIM21 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human TRIM21 Gene Overview
| Gene Name | tripartite motif containing 21 |
|---|---|
| Gene Symbol | TRIM21 |
| Synonyms | SSA,RO52,SSA1,RNF81,Ro/SSA |
| NCBI ID | 6737 |
| Ensembl ID | ENSG00000132109 |
| Uniprot ID | P19474 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
Human TRIM21 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC147754 | View Product |
| AAV Vector & Virus | Long-term expression | VC147754 | View Product |
| Adenovirus | Transient expression | A147754 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG147754 | View Product |
| Gene knockout (non-viral) | PG147754 | View Product | |
| Gene knockout (AAV) | VG147754 | View Product | |
| CRISPR Activation | Gene activation | LA147754 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS147754 | View Product |
| Gene knockdown (AAV) | VS147754 | View Product | |
| ORF Vector | Template DNA | PC147754 | View Product |
Mouse Trim21 Gene Overview
| Gene Name | tripartite motif-containing 21 |
|---|---|
| Gene Symbol | Trim21 |
| Synonyms | Ro52,Ssa1 |
| NCBI ID | 20821 |
| Ensembl ID | ENSMUSG00000030966 |
| Uniprot ID | Q62191 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable identical protein binding activity; transcription coactivator activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including defense response to other organism; protein ubiquitination; and regulation of DNA-binding transcription factor activity. Located in cytoplasm. Is expressed in central nervous system; genitourinary system; retina; and thymus primordium. Orthologous to human TRIM21 (tripartite motif containing 21). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Trim21 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC447754 | View Product |
| Stable overexpression | LC547754 | View Product | |
| AAV Vector & Virus | Long-term expression | VC447754 | View Product |
| Long-term expression | VC547754 | View Product | |
| Adenovirus | Transient expression | A447754 | View Product |
| Transient expression | A547754 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG447754 | View Product |
| Gene knockout (non-viral) | PG447754 | View Product | |
| Gene knockout (AAV) | VG447754 | View Product | |
| CRISPR Activation | Gene activation | LA447754 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS447754 | View Product |
| Gene knockdown (AAV) | VS447754 | View Product | |
| ORF Vector | Template DNA | PC447754 | View Product |
| Template DNA | PC547754 | View Product |
Rat Trim21 Gene Overview
| Gene Name | tripartite motif-containing 21 |
|---|---|
| Gene Symbol | Trim21 |
| Synonyms | |
| NCBI ID | 308901 |
| Ensembl ID | ENSRNOG00000018517 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable identical protein binding activity; transcription coactivator activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including defense response to other organism; protein ubiquitination; and regulation of DNA-binding transcription factor activity. Predicted to be located in nucleus. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytoplasmic stress granule and nucleoplasm. Orthologous to human TRIM21 (tripartite motif containing 21). [provided by Alliance of Genome Resources, Apr 2025]
Rat Trim21 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC647754 | View Product |
| AAV Vector & Virus | Long-term expression | VC647754 | View Product |
| Adenovirus | Transient expression | A647754 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG647754 | View Product |
| Gene knockout (non-viral) | PG647754 | View Product | |
| Gene knockout (AAV) | VG647754 | View Product | |
| CRISPR Activation | Gene activation | LA647754 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS647754 | View Product |
| Gene knockdown (AAV) | VS647754 | View Product | |
| ORF Vector | Template DNA | PC647754 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |