TRIM28 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use TRIM28-specific vectors and viral particles designed for reliable TRIM28 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including TRIM28 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human TRIM28 Gene Overview
| Gene Name | tripartite motif containing 28 |
|---|---|
| Gene Symbol | TRIM28 |
| Synonyms | WT7,KAP1,TF1B,RNF96,TIF1B,PPP1R157,TIF1beta |
| NCBI ID | 10155 |
| Ensembl ID | ENSG00000130726 |
| Uniprot ID | Q13263 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008]
Human TRIM28 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC147762 | View Product |
| AAV Vector & Virus | Long-term expression | VC147762 | View Product |
| Adenovirus | Transient expression | A147762 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG147762 | View Product |
| Gene knockout (non-viral) | PG147762 | View Product | |
| Gene knockout (AAV) | VG147762 | View Product | |
| CRISPR Activation | Gene activation | LA147762 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS147762 | View Product |
| Gene knockdown (AAV) | VS147762 | View Product | |
| ORF Vector | Template DNA | PC147762 | View Product |
Mouse Trim28 Gene Overview
| Gene Name | tripartite motif-containing 28 |
|---|---|
| Gene Symbol | Trim28 |
| Synonyms | KAP-1,Tif1b,KRIP-1,MommeD9,Tif1beta |
| NCBI ID | 21849 |
| Ensembl ID | ENSMUSG00000005566 |
| Uniprot ID | Q62318 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA binding activity; protein kinase activity; and transcription coactivator activity. Involved in DNA methylation-dependent constitutive heterochromatin formation; epithelial to mesenchymal transition; and positive regulation of DNA-templated transcription. Acts upstream of or within several processes, including convergent extension involved in axis elongation; embryo implantation; and negative regulation of RNA biosynthetic process. Located in euchromatin; heterochromatin; and nucleoplasm. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; genitourinary system; and limb primordium. Orthologous to human TRIM28 (tripartite motif containing 28). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Trim28 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC447762 | View Product |
| AAV Vector & Virus | Long-term expression | VC447762 | View Product |
| Adenovirus | Transient expression | A447762 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG447762 | View Product |
| Gene knockout (non-viral) | PG447762 | View Product | |
| Gene knockout (AAV) | VG447762 | View Product | |
| CRISPR Activation | Gene activation | LA447762 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS447762 | View Product |
| Gene knockdown (AAV) | VS447762 | View Product | |
| ORF Vector | Template DNA | PC447762 | View Product |
Rat Trim28 Gene Overview
| Gene Name | tripartite motif-containing 28 |
|---|---|
| Gene Symbol | Trim28 |
| Synonyms | Kap1,Krip1,Tif1b |
| NCBI ID | 116698 |
| Ensembl ID | ENSRNOG00000027487 |
| Uniprot ID | O08629 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including protein domain specific binding activity; transcription coregulator activity; and ubiquitin-like protein transferase activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of protein import into nucleus; and regulation of macromolecule metabolic process. Predicted to act upstream of or within several processes, including convergent extension involved in axis elongation; embryo implantation; and negative regulation of RNA biosynthetic process. Predicted to be located in euchromatin; heterochromatin; and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Orthologous to human TRIM28 (tripartite motif containing 28). [provided by Alliance of Genome Resources, Apr 2025]
Rat Trim28 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC647762 | View Product |
| AAV Vector & Virus | Long-term expression | VC647762 | View Product |
| Adenovirus | Transient expression | A647762 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG647762 | View Product |
| Gene knockout (non-viral) | PG647762 | View Product | |
| Gene knockout (AAV) | VG647762 | View Product | |
| CRISPR Activation | Gene activation | LA647762 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS647762 | View Product |
| Gene knockdown (AAV) | VS647762 | View Product | |
| ORF Vector | Template DNA | PC647762 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |