TRPV1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use TRPV1-specific vectors and viral particles designed for reliable TRPV1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including TRPV1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human TRPV1 Gene Overview
| Gene Name | transient receptor potential cation channel subfamily V member 1 |
|---|---|
| Gene Symbol | TRPV1 |
| Synonyms | VR1 |
| NCBI ID | 7442 |
| Ensembl ID | ENSG00000196689 |
| Uniprot ID | Q8NER1 |
| Gene Type | Protein coding |
Gene Summary
Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
Human TRPV1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC148530 | View Product |
| AAV Vector & Virus | Long-term expression | VC148530 | View Product |
| Adenovirus | Transient expression | A148530 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG148530 | View Product |
| Gene knockout (non-viral) | PG148530 | View Product | |
| Gene knockout (AAV) | VG148530 | View Product | |
| CRISPR Activation | Gene activation | LA148530 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS148530 | View Product |
| Gene knockdown (AAV) | VS148530 | View Product | |
| ORF Vector | Template DNA | PC148530 | View Product |
Mouse Trpv1 Gene Overview
| Gene Name | transient receptor potential cation channel, subfamily V, member 1 |
|---|---|
| Gene Symbol | Trpv1 |
| Synonyms | Vr1,VR-1,OTRPC1,TRPV1beta,TRPV1alpha |
| NCBI ID | 193034 |
| Ensembl ID | ENSMUSG00000005952 |
| Uniprot ID | Q704Y3 |
| Gene Type | Protein coding |
Gene Summary
Enables calcium channel activity; identical protein binding activity; and temperature-gated ion channel activity. Involved in detection of temperature stimulus involved in sensory perception of pain; monoatomic ion transmembrane transport; and negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including diet induced thermogenesis; fever generation; and sensory perception of chemical stimulus. Located in neuron projection and plasma membrane. Is active in GABA-ergic synapse and postsynaptic membrane. Is expressed in central nervous system; cochlea; dorsal root ganglion; and eye. Human ortholog(s) of this gene implicated in migraine. Orthologous to human TRPV1 (transient receptor potential cation channel subfamily V member 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Trpv1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC448530 | View Product |
| AAV Vector & Virus | Long-term expression | VC448530 | View Product |
| Adenovirus | Transient expression | A448530 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG448530 | View Product |
| Gene knockout (non-viral) | PG448530 | View Product | |
| Gene knockout (AAV) | VG448530 | View Product | |
| CRISPR Activation | Gene activation | LA448530 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS448530 | View Product |
| Gene knockdown (AAV) | VS448530 | View Product | |
| ORF Vector | Template DNA | PC448530 | View Product |
Rat Trpv1 Gene Overview
| Gene Name | transient receptor potential cation channel, subfamily V, member 1 |
|---|---|
| Gene Symbol | Trpv1 |
| Synonyms | Vr1,Vr1l1,VR.5'sv,TRPV1_SON |
| NCBI ID | 83810 |
| Ensembl ID | ENSRNOG00000019486 |
| Uniprot ID | O35433 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including ATP binding activity; calmodulin binding activity; and ligand-gated monoatomic ion channel activity. Involved in several processes, including calcium ion import across plasma membrane; cellular response to temperature stimulus; and negative regulation of establishment of blood-brain barrier. Acts upstream of or within response to heat and response to pH. Located in dendrite; external side of plasma membrane; and neuronal cell body. Is active in postsynaptic membrane. Used to study myocardial infarction and reflex epilepsy. Human ortholog(s) of this gene implicated in migraine. Orthologous to human TRPV1 (transient receptor potential cation channel subfamily V member 1). [provided by Alliance of Genome Resources, Apr 2025]
Rat Trpv1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC648530 | View Product |
| AAV Vector & Virus | Long-term expression | VC648530 | View Product |
| Adenovirus | Transient expression | A648530 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG648530 | View Product |
| Gene knockout (non-viral) | PG648530 | View Product | |
| Gene knockout (AAV) | VG648530 | View Product | |
| CRISPR Activation | Gene activation | LA648530 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS648530 | View Product |
| Gene knockdown (AAV) | VS648530 | View Product | |
| ORF Vector | Template DNA | PC648530 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |