TXNIP Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use TXNIP-specific vectors and viral particles designed for reliable TXNIP overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including TXNIP CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human TXNIP Gene Overview
| Gene Name | thioredoxin interacting protein |
|---|---|
| Gene Symbol | TXNIP |
| Synonyms | THIF,VDUP1,ARRDC6,HHCPA78,EST01027 |
| NCBI ID | 10628 |
| Ensembl ID | ENSG00000265972 |
| Uniprot ID | Q9H3M7 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Human TXNIP Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC148879 | View Product |
| AAV Vector & Virus | Long-term expression | VC148879 | View Product |
| Adenovirus | Transient expression | A148879 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG148879 | View Product |
| Gene knockout (non-viral) | PG148879 | View Product | |
| Gene knockout (AAV) | VG148879 | View Product | |
| CRISPR Activation | Gene activation | LA148879 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS148879 | View Product |
| Gene knockdown (AAV) | VS148879 | View Product | |
| ORF Vector | Template DNA | PC148879 | View Product |
Mouse Txnip Gene Overview
| Gene Name | thioredoxin interacting protein |
|---|---|
| Gene Symbol | Txnip |
| Synonyms | THIF,Tbp-2,VDUP1,Hyplip1,1200008J08Rik |
| NCBI ID | 56338 |
| Ensembl ID | ENSMUSG00000038393 |
| Uniprot ID | Q8BG60 |
| Gene Type | Protein coding |
Gene Summary
Enables enzyme inhibitor activity. Acts upstream of or within several processes, including negative regulation of transcription by RNA polymerase II; platelet-derived growth factor receptor signaling pathway; and protein import into nucleus. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Used to study Reye syndrome and hepatocellular carcinoma. Orthologous to human TXNIP (thioredoxin interacting protein). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Txnip Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC448879 | View Product |
| Stable overexpression | LC548879 | View Product | |
| AAV Vector & Virus | Long-term expression | VC448879 | View Product |
| Long-term expression | VC548879 | View Product | |
| Adenovirus | Transient expression | A448879 | View Product |
| Transient expression | A548879 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG448879 | View Product |
| Gene knockout (non-viral) | PG448879 | View Product | |
| Gene knockout (AAV) | VG448879 | View Product | |
| CRISPR Activation | Gene activation | LA448879 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS448879 | View Product |
| Gene knockdown (AAV) | VS448879 | View Product | |
| ORF Vector | Template DNA | PC448879 | View Product |
| Template DNA | PC548879 | View Product |
Rat Txnip Gene Overview
| Gene Name | thioredoxin interacting protein |
|---|---|
| Gene Symbol | Txnip |
| Synonyms | Vdup1 |
| NCBI ID | 117514 |
| Ensembl ID | ENSRNOG00000021201 |
| Uniprot ID | Q5M7W1 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable enzyme inhibitor activity and ubiquitin protein ligase binding activity. Involved in several processes, including response to estradiol; response to hydrogen peroxide; and response to progesterone. Predicted to be active in cytoplasm. Used to study renal cell carcinoma. Biomarker of colorectal cancer; glaucoma; and stomach cancer. Orthologous to human TXNIP (thioredoxin interacting protein). [provided by Alliance of Genome Resources, Jul 2025]
Rat Txnip Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC648879 | View Product |
| AAV Vector & Virus | Long-term expression | VC648879 | View Product |
| Adenovirus | Transient expression | A648879 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG648879 | View Product |
| Gene knockout (non-viral) | PG648879 | View Product | |
| Gene knockout (AAV) | VG648879 | View Product | |
| CRISPR Activation | Gene activation | LA648879 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS648879 | View Product |
| Gene knockdown (AAV) | VS648879 | View Product | |
| ORF Vector | Template DNA | PC648879 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |