ULK1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use ULK1-specific vectors and viral particles designed for reliable ULK1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including ULK1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human ULK1 Gene Overview
| Gene Name | unc-51 like autophagy activating kinase 1 |
|---|---|
| Gene Symbol | ULK1 |
| Synonyms | ATG1,ATG1A,UNC51,hATG1,Unc51.1 |
| NCBI ID | 8408 |
| Ensembl ID | ENSG00000177169 |
| Uniprot ID | O75385 |
| Gene Type | Protein coding |
Gene Summary
Enables identical protein binding activity; protein serine/threonine kinase activity; and small GTPase binding activity. Involved in several processes, including autophagosome assembly; protein phosphorylation; and regulation of autophagy. Located in bounding membrane of organelle; cytosol; and phagophore assembly site membrane. Part of Atg1/ULK1 kinase complex. Is active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Human ULK1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC149161 | View Product |
| AAV Vector & Virus | Long-term expression | VC149161 | View Product |
| Adenovirus | Transient expression | A149161 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG149161 | View Product |
| Gene knockout (non-viral) | PG149161 | View Product | |
| Gene knockout (AAV) | VG149161 | View Product | |
| CRISPR Activation | Gene activation | LA149161 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS149161 | View Product |
| Gene knockdown (AAV) | VS149161 | View Product | |
| ORF Vector | Template DNA | PC149161 | View Product |
Mouse Ulk1 Gene Overview
| Gene Name | unc-51 like kinase 1 |
|---|---|
| Gene Symbol | Ulk1 |
| Synonyms | Unc51.1,mKIAA0722 |
| NCBI ID | 22241 |
| Ensembl ID | ENSMUSG00000029512 |
| Uniprot ID | O70405 |
| Gene Type | Protein coding |
Gene Summary
Enables Hsp90 protein binding activity; protein kinase binding activity; and protein serine/threonine kinase activity. Involved in several processes, including cellular response to amino acid starvation; macroautophagy; and response to mitochondrial depolarisation. Acts upstream of or within several processes, including Ras protein signal transduction; generation of neurons; and radial glia guided migration of cerebellar granule cell. Located in several cellular components, including cytoplasmic vesicle membrane; neuronal cell body; and phagophore assembly site membrane. Part of Atg1/ULK1 kinase complex. Is expressed in several structures, including central nervous system; dorsal root ganglion; heart; retina; and tibialis anterior. Orthologous to human ULK1 (unc-51 like autophagy activating kinase 1). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Ulk1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC449161 | View Product |
| AAV Vector & Virus | Long-term expression | VC449161 | View Product |
| Adenovirus | Transient expression | A449161 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG449161 | View Product |
| Gene knockout (non-viral) | PG449161 | View Product | |
| Gene knockout (AAV) | VG449161 | View Product | |
| CRISPR Activation | Gene activation | LA449161 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS449161 | View Product |
| Gene knockdown (AAV) | VS449161 | View Product | |
| ORF Vector | Template DNA | PC449161 | View Product |
Rat Ulk1 Gene Overview
| Gene Name | unc-51 like autophagy activating kinase 1 |
|---|---|
| Gene Symbol | Ulk1 |
| Synonyms | |
| NCBI ID | 360827 |
| Ensembl ID | ENSRNOG00000037505 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including Hsp90 protein binding activity; enzyme binding activity; and identical protein binding activity. Involved in neuron projection regeneration and positive regulation of autophagosome assembly. Located in axon. Used to study mucositis. Biomarker of metabolic dysfunction-associated steatohepatitis. Orthologous to human ULK1 (unc-51 like autophagy activating kinase 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Ulk1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC649161 | View Product |
| AAV Vector & Virus | Long-term expression | VC649161 | View Product |
| Adenovirus | Transient expression | A649161 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG649161 | View Product |
| Gene knockout (non-viral) | PG649161 | View Product | |
| Gene knockout (AAV) | VG649161 | View Product | |
| CRISPR Activation | Gene activation | LA649161 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS649161 | View Product |
| Gene knockdown (AAV) | VS649161 | View Product | |
| ORF Vector | Template DNA | PC649161 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |