VTCN1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use VTCN1-specific vectors and viral particles designed for reliable VTCN1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including VTCN1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human VTCN1 Gene Overview
| Gene Name | V-set domain containing T cell activation inhibitor 1 |
|---|---|
| Gene Symbol | VTCN1 |
| Synonyms | B7X,B7H4,B7S1,B7-H4,B7h.5,VCTN1,PRO1291 |
| NCBI ID | 79679 |
| Ensembl ID | ENSG00000134258 |
| Uniprot ID | Q7Z7D3 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Human VTCN1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC150219 | View Product |
| AAV Vector & Virus | Long-term expression | VC150219 | View Product |
| Adenovirus | Transient expression | A150219 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG150219 | View Product |
| Gene knockout (non-viral) | PG150219 | View Product | |
| Gene knockout (AAV) | VG150219 | View Product | |
| CRISPR Activation | Gene activation | LA150219 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS150219 | View Product |
| Gene knockdown (AAV) | VS150219 | View Product | |
| ORF Vector | Template DNA | PC150219 | View Product |
Mouse Vtcn1 Gene Overview
| Gene Name | V-set domain containing T cell activation inhibitor 1 |
|---|---|
| Gene Symbol | Vtcn1 |
| Synonyms | B7x,B7h4,B7s1 |
| NCBI ID | 242122 |
| Ensembl ID | ENSMUSG00000051076 |
| Uniprot ID | Q7TSP5 |
| Gene Type | Protein coding |
Gene Summary
Enables signaling receptor binding activity. Acts upstream of or within positive regulation of interleukin-2 production; regulation of T cell activation; and response to protozoan. Located in external side of plasma membrane. Is expressed in several structures, including hemolymphoid system gland; liver; lung; male reproductive gland or organ; and pancreas. Orthologous to human VTCN1 (V-set domain containing T cell activation inhibitor 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Vtcn1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC450219 | View Product |
| AAV Vector & Virus | Long-term expression | VC450219 | View Product |
| Adenovirus | Transient expression | A450219 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG450219 | View Product |
| Gene knockout (non-viral) | PG450219 | View Product | |
| Gene knockout (AAV) | VG450219 | View Product | |
| CRISPR Activation | Gene activation | LA450219 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS450219 | View Product |
| Gene knockdown (AAV) | VS450219 | View Product | |
| ORF Vector | Template DNA | PC450219 | View Product |
Rat Vtcn1 Gene Overview
| Gene Name | V-set domain containing T cell activation inhibitor 1 |
|---|---|
| Gene Symbol | Vtcn1 |
| Synonyms | RGD1311204 |
| NCBI ID | 295322 |
| Ensembl ID | ENSRNOG00000015279 |
| Uniprot ID | Q501W4 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable signaling receptor binding activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; negative regulation of T cell proliferation; and negative regulation of apoptotic process. Predicted to act upstream of or within positive regulation of interleukin-2 production; regulation of T cell activation; and response to protozoan. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Orthologous to human VTCN1 (V-set domain containing T cell activation inhibitor 1). [provided by Alliance of Genome Resources, Apr 2025]
Rat Vtcn1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC650219 | View Product |
| AAV Vector & Virus | Long-term expression | VC650219 | View Product |
| Adenovirus | Transient expression | A650219 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG650219 | View Product |
| Gene knockout (non-viral) | PG650219 | View Product | |
| Gene knockout (AAV) | VG650219 | View Product | |
| CRISPR Activation | Gene activation | LA650219 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS650219 | View Product |
| Gene knockdown (AAV) | VS650219 | View Product | |
| ORF Vector | Template DNA | PC650219 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |