WNT5A Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use WNT5A-specific vectors and viral particles designed for reliable WNT5A overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including WNT5A CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human WNT5A Gene Overview
| Gene Name | Wnt family member 5A |
|---|---|
| Gene Symbol | WNT5A |
| Synonyms | hWNT5A |
| NCBI ID | 7474 |
| Ensembl ID | ENSG00000114251 |
| Uniprot ID | P41221 |
| Gene Type | Protein coding |
Gene Summary
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Human WNT5A Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC150453 | View Product |
| AAV Vector & Virus | Long-term expression | VC150453 | View Product |
| Adenovirus | Transient expression | A150453 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG150453 | View Product |
| Gene knockout (non-viral) | PG150453 | View Product | |
| Gene knockout (AAV) | VG150453 | View Product | |
| CRISPR Activation | Gene activation | LA150453 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS150453 | View Product |
| Gene knockdown (AAV) | VS150453 | View Product | |
| ORF Vector | Template DNA | PC150453 | View Product |
Mouse Wnt5a Gene Overview
| Gene Name | wingless-type MMTV integration site family, member 5A |
|---|---|
| Gene Symbol | Wnt5a |
| Synonyms | Wnt-5a,8030457G12Rik |
| NCBI ID | 22418 |
| Ensembl ID | ENSMUSG00000021994 |
| Uniprot ID | P22725 |
| Gene Type | Protein coding |
Gene Summary
Enables frizzled binding activity; protein domain specific binding activity; and receptor ligand activity. Involved in several processes, including heart development; neuron differentiation; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including embryonic morphogenesis; morphogenesis of an epithelium; and reproductive structure development. Located in cell surface and extracellular matrix. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including alimentary system; embryo ectoderm; genitourinary system; limb; and sensory organ. Used to study Robinow syndrome. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 1. Orthologous to human WNT5A (Wnt family member 5A). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Wnt5a Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC450453 | View Product |
| Stable overexpression | LC550453 | View Product | |
| AAV Vector & Virus | Long-term expression | VC450453 | View Product |
| Long-term expression | VC550453 | View Product | |
| Adenovirus | Transient expression | A450453 | View Product |
| Transient expression | A550453 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG450453 | View Product |
| Gene knockout (non-viral) | PG450453 | View Product | |
| Gene knockout (AAV) | VG450453 | View Product | |
| CRISPR Activation | Gene activation | LA450453 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS450453 | View Product |
| Gene knockdown (AAV) | VS450453 | View Product | |
| ORF Vector | Template DNA | PC450453 | View Product |
| Template DNA | PC550453 | View Product |
Rat Wnt5a Gene Overview
| Gene Name | Wnt family member 5A |
|---|---|
| Gene Symbol | Wnt5a |
| Synonyms | |
| NCBI ID | 64566 |
| Ensembl ID | ENSRNOG00000015618 |
| Uniprot ID | Q9QXQ7 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable protein domain specific binding activity and signaling receptor binding activity. Involved in several processes, including estrous cycle; regulation of cell morphogenesis; and regulation of synaptic signaling by nitric oxide. Acts upstream of or within Wnt signaling pathway, planar cell polarity pathway. Located in extracellular space. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Biomarker of colon cancer. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 1. Orthologous to human WNT5A (Wnt family member 5A). [provided by Alliance of Genome Resources, Jul 2025]
Rat Wnt5a Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC650453 | View Product |
| AAV Vector & Virus | Long-term expression | VC650453 | View Product |
| Adenovirus | Transient expression | A650453 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG650453 | View Product |
| Gene knockout (non-viral) | PG650453 | View Product | |
| Gene knockout (AAV) | VG650453 | View Product | |
| CRISPR Activation | Gene activation | LA650453 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS650453 | View Product |
| Gene knockdown (AAV) | VS650453 | View Product | |
| ORF Vector | Template DNA | PC650453 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |