WWTR1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use WWTR1-specific vectors and viral particles designed for reliable WWTR1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including WWTR1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human WWTR1 Gene Overview
| Gene Name | WW domain containing transcription regulator 1 |
|---|---|
| Gene Symbol | WWTR1 |
| Synonyms | TAZ |
| NCBI ID | 25937 |
| Ensembl ID | ENSG00000018408 |
| Uniprot ID | Q9GZV5 |
| Gene Type | Protein coding |
Gene Summary
Enables transcription coactivator activity. Involved in several processes, including intracellular signal transduction; negative regulation of canonical Wnt signaling pathway; and positive regulation of cell differentiation. Located in cytosol and nuclear body. Is active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Human WWTR1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC150490 | View Product |
| AAV Vector & Virus | Long-term expression | VC150490 | View Product |
| Adenovirus | Transient expression | A150490 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG150490 | View Product |
| Gene knockout (non-viral) | PG150490 | View Product | |
| Gene knockout (AAV) | VG150490 | View Product | |
| CRISPR Activation | Gene activation | LA150490 | View Product |
| siRNA Tools | Gene knockdown (AAV) | VS150490 | View Product |
| ORF Vector | Template DNA | PC150490 | View Product |
Mouse Wwtr1 Gene Overview
| Gene Name | WW domain containing transcription regulator 1 |
|---|---|
| Gene Symbol | Wwtr1 |
| Synonyms | Taz,2310058J06Rik,2610021I22Rik |
| NCBI ID | 97064 |
| Ensembl ID | ENSMUSG00000027803 |
| Uniprot ID | Q9EPK5 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
Mouse Wwtr1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC450490 | View Product |
| Stable overexpression | LC550490 | View Product | |
| AAV Vector & Virus | Long-term expression | VC450490 | View Product |
| Long-term expression | VC550490 | View Product | |
| Adenovirus | Transient expression | A450490 | View Product |
| Transient expression | A550490 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG450490 | View Product |
| Gene knockout (non-viral) | PG450490 | View Product | |
| Gene knockout (AAV) | VG450490 | View Product | |
| CRISPR Activation | Gene activation | LA450490 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS450490 | View Product |
| Gene knockdown (AAV) | VS450490 | View Product | |
| ORF Vector | Template DNA | PC450490 | View Product |
| Template DNA | PC550490 | View Product |
Rat Wwtr1 Gene Overview
| Gene Name | WW domain containing transcription regulator 1 |
|---|---|
| Gene Symbol | Wwtr1 |
| Synonyms | |
| NCBI ID | 295062 |
| Ensembl ID | ENSRNOG00000016617 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable protein homodimerization activity; transcription coactivator activity; and transcription corepressor activity. Predicted to be involved in several processes, including intracellular signal transduction; negative regulation of canonical Wnt signaling pathway; and positive regulation of cell differentiation. Predicted to act upstream of or within several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; kidney development; and negative regulation of fat cell differentiation. Located in nucleus. Orthologous to human WWTR1 (WW domain containing transcription regulator 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Wwtr1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC650490 | View Product |
| AAV Vector & Virus | Long-term expression | VC650490 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG650490 | View Product |
| Gene knockout (non-viral) | PG650490 | View Product | |
| Gene knockout (AAV) | VG650490 | View Product | |
| CRISPR Activation | Gene activation | LA650490 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS650490 | View Product |
| Gene knockdown (AAV) | VS650490 | View Product | |
| ORF Vector | Template DNA | PC650490 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |