YAP1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use YAP1-specific vectors and viral particles designed for reliable YAP1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including YAP1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human YAP1 Gene Overview
| Gene Name | Yes1 associated transcriptional regulator |
|---|---|
| Gene Symbol | YAP1 |
| Synonyms | YAP,YKI,COB1,YAP2,YAP-1,YAP65 |
| NCBI ID | 10413 |
| Ensembl ID | ENSG00000137693 |
| Uniprot ID | P46937 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]
Human YAP1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC150584 | View Product |
| AAV Vector & Virus | Long-term expression | VC150584 | View Product |
| Adenovirus | Transient expression | A150584 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG150584 | View Product |
| Gene knockout (non-viral) | PG150584 | View Product | |
| Gene knockout (AAV) | VG150584 | View Product | |
| CRISPR Activation | Gene activation | LA150584 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS150584 | View Product |
| Gene knockdown (AAV) | VS150584 | View Product | |
| ORF Vector | Template DNA | PC150584 | View Product |
Mouse Yap1 Gene Overview
| Gene Name | yes-associated protein 1 |
|---|---|
| Gene Symbol | Yap1 |
| Synonyms | Yap,Yki,Yap65,Yorkie |
| NCBI ID | 22601 |
| Ensembl ID | ENSMUSG00000053110 |
| Uniprot ID | P46938 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a protein which binds to the SH3 domain of the Yes proto-oncogene product, a tyrosine kinase. This protein contains a WW domain, consisting of four conserved aromatic amino acids including two tryptophan residues. This conserved WW domain is found in various structural, regulatory and signaling molecules in various species, and may play a role in protein-protein interaction. Following cellular damage, phosphorylation of this encoded protein may suppress apoptosis. This protein may be involved in malignant transformation in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Mouse Yap1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC450584 | View Product |
| Stable overexpression | LC550584 | View Product | |
| AAV Vector & Virus | Long-term expression | VC450584 | View Product |
| Long-term expression | VC550584 | View Product | |
| Adenovirus | Transient expression | A450584 | View Product |
| Transient expression | A550584 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG450584 | View Product |
| Gene knockout (non-viral) | PG450584 | View Product | |
| Gene knockout (AAV) | VG450584 | View Product | |
| CRISPR Activation | Gene activation | LA450584 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS450584 | View Product |
| Gene knockdown (AAV) | VS450584 | View Product | |
| ORF Vector | Template DNA | PC450584 | View Product |
| Template DNA | PC550584 | View Product |
Rat Yap1 Gene Overview
| Gene Name | Yes1 associated transcriptional regulator |
|---|---|
| Gene Symbol | Yap1 |
| Synonyms | Yap,YAP65 |
| NCBI ID | 363014 |
| Ensembl ID | ENSRNOG00000005933 |
| Uniprot ID | Q2EJA0 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; proline-rich region binding activity; and transcription coregulator activity. Predicted to be involved in several processes, including cardiac muscle tissue regeneration; intracellular signal transduction; and regulation of gene expression. Predicted to act upstream of or within several processes, including regulation of epithelial cell differentiation; regulation of epithelial cell proliferation; and tube morphogenesis. Predicted to be located in several cellular components, including mitochondrion; nucleus; and tight junction. Predicted to be part of TEAD-YAP complex. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in uveal coloboma-cleft lip and palate-intellectual disability. Orthologous to human YAP1 (Yes1 associated transcriptional regulator). [provided by Alliance of Genome Resources, Jul 2025]
Rat Yap1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |