YBX1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use YBX1-specific vectors and viral particles designed for reliable YBX1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including YBX1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human YBX1 Gene Overview
| Gene Name | Y-box binding protein 1 |
|---|---|
| Gene Symbol | YBX1 |
| Synonyms | YB1,BP-8,CSDB,DBPB,YB-1,CBF-A,CSDA2,EFI-A,NSEP1,NSEP-1,MDR-NF1 |
| NCBI ID | 4904 |
| Ensembl ID | ENSG00000065978 |
| Uniprot ID | P67809 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]
Human YBX1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC150590 | View Product |
| AAV Vector & Virus | Long-term expression | VC150590 | View Product |
| Adenovirus | Transient expression | A150590 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG150590 | View Product |
| Gene knockout (non-viral) | PG150590 | View Product | |
| Gene knockout (AAV) | VG150590 | View Product | |
| CRISPR Activation | Gene activation | LA150590 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS150590 | View Product |
| Gene knockdown (AAV) | VS150590 | View Product | |
| ORF Vector | Template DNA | PC150590 | View Product |
Mouse Ybx1 Gene Overview
| Gene Name | Y box protein 1 |
|---|---|
| Gene Symbol | Ybx1 |
| Synonyms | EF1A,MSY1,YB-1,dbpB,Nsep1,mYB-1a,1700102N10Rik |
| NCBI ID | 22608 |
| Ensembl ID | ENSMUSG00000028639 |
| Uniprot ID | P62960 |
| Gene Type | Protein coding |
Gene Summary
Enables chromatin binding activity; mRNA binding activity; and single-stranded DNA binding activity. Involved in epidermis development and negative regulation of cellular senescence. Acts upstream of or within several processes, including cellular response to interleukin-7; negative regulation of striated muscle cell differentiation; and negative regulation of transcription by RNA polymerase II. Located in P-body and nucleus. Part of histone pre-mRNA 3'end processing complex. Is active in synapse. Is expressed in several structures, including brain; branchial arch; facial prominence; gonad; and retina. Orthologous to human YBX1 (Y-box binding protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Ybx1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC450590 | View Product |
| AAV Vector & Virus | Long-term expression | VC450590 | View Product |
| Adenovirus | Transient expression | A450590 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG450590 | View Product |
| Gene knockout (non-viral) | PG450590 | View Product | |
| Gene knockout (AAV) | VG450590 | View Product | |
| CRISPR Activation | Gene activation | LA450590 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS450590 | View Product |
| Gene knockdown (AAV) | VS450590 | View Product | |
| ORF Vector | Template DNA | PC450590 | View Product |
Rat Ybx1 Gene Overview
| Gene Name | Y box binding protein 1 |
|---|---|
| Gene Symbol | Ybx1 |
| Synonyms | Yb1,Byb1,Cbfa,Dbpb,Ef1a,Msy1,YB-1,CBF-A,EFI-A,Nsep1 |
| NCBI ID | 500538 |
| Ensembl ID | ENSRNOG00000023786 |
| Uniprot ID | P62961 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA binding activity; mRNA binding activity; and p53 binding activity. Involved in several processes, including negative regulation of apoptotic process; negative regulation of insulin receptor signaling pathway; and regulation of transcription by RNA polymerase II. Located in dendrite; neuronal cell body; and perinuclear region of cytoplasm. Part of protein-containing complex. Biomarker of myocardial infarction. Orthologous to human YBX1 (Y-box binding protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Ybx1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC650590 | View Product |
| AAV Vector & Virus | Long-term expression | VC650590 | View Product |
| Adenovirus | Transient expression | A650590 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG650590 | View Product |
| Gene knockout (non-viral) | PG650590 | View Product | |
| Gene knockout (AAV) | VG650590 | View Product | |
| CRISPR Activation | Gene activation | LA650590 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS650590 | View Product |
| Gene knockdown (AAV) | VS650590 | View Product | |
| ORF Vector | Template DNA | PC650590 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |