YTHDF2 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use YTHDF2-specific vectors and viral particles designed for reliable YTHDF2 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including YTHDF2 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human YTHDF2 Gene Overview
| Gene Name | YTH N6-methyladenosine RNA binding protein F2 |
|---|---|
| Gene Symbol | YTHDF2 |
| Synonyms | DF2,CAHL,HGRG8,NY-REN-2 |
| NCBI ID | 51441 |
| Ensembl ID | ENSG00000198492 |
| Uniprot ID | Q9Y5A9 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Oct 2012]
Human YTHDF2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC150638 | View Product |
| AAV Vector & Virus | Long-term expression | VC150638 | View Product |
| Adenovirus | Transient expression | A150638 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG150638 | View Product |
| Gene knockout (non-viral) | PG150638 | View Product | |
| Gene knockout (AAV) | VG150638 | View Product | |
| CRISPR Activation | Gene activation | LA150638 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS150638 | View Product |
| Gene knockdown (AAV) | VS150638 | View Product | |
| ORF Vector | Template DNA | PC150638 | View Product |
Mouse Ythdf2 Gene Overview
| Gene Name | YTH N6-methyladenosine RNA binding protein 2 |
|---|---|
| Gene Symbol | Ythdf2 |
| Synonyms | HGRG8,NY-REN-2,9430020E02Rik |
| NCBI ID | 213541 |
| Ensembl ID | ENSMUSG00000040025 |
| Uniprot ID | Q91YT7 |
| Gene Type | Protein coding |
Gene Summary
Enables N6-methyladenosine-containing RNA reader activity. Involved in several processes, including hematopoietic stem cell proliferation; negative regulation of gene expression; and spermatogonial cell division. Located in cytoplasm and nucleus. Is expressed in brain; intestine; and liver. Orthologous to human YTHDF2 (YTH N6-methyladenosine RNA binding protein F2). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Ythdf2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC450638 | View Product |
| AAV Vector & Virus | Long-term expression | VC450638 | View Product |
| Adenovirus | Transient expression | A450638 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG450638 | View Product |
| Gene knockout (non-viral) | PG450638 | View Product | |
| Gene knockout (AAV) | VG450638 | View Product | |
| CRISPR Activation | Gene activation | LA450638 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS450638 | View Product |
| Gene knockdown (AAV) | VS450638 | View Product | |
| ORF Vector | Template DNA | PC450638 | View Product |
Rat Ythdf2 Gene Overview
| Gene Name | YTH N6-methyladenosine RNA binding protein F2 |
|---|---|
| Gene Symbol | Ythdf2 |
| Synonyms | |
| NCBI ID | 313053 |
| Ensembl ID | ENSRNOG00000010892 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable C5-methylcytidine-containing RNA reader activity; N6-methyladenosine-containing RNA reader activity; and mRNA binding activity. Predicted to be involved in several processes, including hematopoietic stem cell proliferation; regulation of gene expression; and regulation of stem cell differentiation. Predicted to be located in several cellular components, including centriolar satellite; cytoplasmic ribonucleoprotein granule; and cytosol. Predicted to be active in cytoplasm. Orthologous to human YTHDF2 (YTH N6-methyladenosine RNA binding protein F2). [provided by Alliance of Genome Resources, Jul 2025]
Rat Ythdf2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC650638 | View Product |
| AAV Vector & Virus | Long-term expression | VC650638 | View Product |
| siRNA Tools | Gene knockdown (AAV) | VS650638 | View Product |
| ORF Vector | Template DNA | PC650638 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |