ZEB2 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use ZEB2-specific vectors and viral particles designed for reliable ZEB2 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including ZEB2 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human ZEB2 Gene Overview
| Gene Name | zinc finger E-box binding homeobox 2 |
|---|---|
| Gene Symbol | ZEB2 |
| Synonyms | SIP1,SIP-1,ZFHX1B,HSPC082,SMADIP1 |
| NCBI ID | 9839 |
| Ensembl ID | ENSG00000169554 |
| Uniprot ID | O60315 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]
Human ZEB2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC150813 | View Product |
| Adenovirus | Transient expression | A150813 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG150813 | View Product |
| Gene knockout (Lentiviral) | LG169151 | View Product | |
| Gene knockout (non-viral) | PG150813 | View Product | |
| Gene knockout (non-viral) | PG169151 | View Product | |
| Gene knockout (AAV) | VG150813 | View Product | |
| Gene knockout (AAV) | VG169151 | View Product | |
| CRISPR Activation | Gene activation | LA150813 | View Product |
| Gene activation | LA169151 | View Product | |
| siRNA Tools | Gene knockdown (Lentiviral) | LS150813 | View Product |
| Gene knockdown (AAV) | VS150813 | View Product | |
| Gene knockdown (AAV) | VS169151 | View Product | |
| ORF Vector | Template DNA | PC150813 | View Product |
Mouse Zeb2 Gene Overview
| Gene Name | zinc finger E-box binding homeobox 2 |
|---|---|
| Gene Symbol | Zeb2 |
| Synonyms | SIP1,Zfx1b,Zfhx1b,Zfxh1b,9130203F04Rik,D130016B08Rik |
| NCBI ID | 24136 |
| Ensembl ID | ENSMUSG00000026872 |
| Uniprot ID | Q9R0G7 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and R-SMAD binding activity. Involved in several processes, including melanocyte migration; positive regulation of cell differentiation; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including nervous system development; positive regulation of axonogenesis; and positive regulation of signal transduction. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study Mowat-Wilson syndrome and T-cell adult acute lymphocytic leukemia. Human ortholog(s) of this gene implicated in Hirschsprung's disease and Mowat-Wilson syndrome. Orthologous to human ZEB2 (zinc finger E-box binding homeobox 2). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Zeb2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC450813 | View Product |
| Adenovirus | Transient expression | A450813 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG450813 | View Product |
| Gene knockout (non-viral) | PG450813 | View Product | |
| Gene knockout (AAV) | VG450813 | View Product | |
| CRISPR Activation | Gene activation | LA450813 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS450813 | View Product |
| Gene knockdown (AAV) | VS450813 | View Product | |
| ORF Vector | Template DNA | PC450813 | View Product |
Rat Zeb2 Gene Overview
| Gene Name | zinc finger E-box binding homeobox 2 |
|---|---|
| Gene Symbol | Zeb2 |
| Synonyms | Zfhx1b |
| NCBI ID | 311071 |
| Ensembl ID | ENSRNOG00000004677 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; R-SMAD binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including myofibroblast differentiation; positive regulation of myofibroblast contraction; and stress fiber assembly. Predicted to be located in chromatin; nuclear lumen; and plasma membrane. Biomarker of myocardial infarction; proteinuria; and rheumatic heart disease. Human ortholog(s) of this gene implicated in Hirschsprung's disease and Mowat-Wilson syndrome. Orthologous to human ZEB2 (zinc finger E-box binding homeobox 2). [provided by Alliance of Genome Resources, Jul 2025]
Rat Zeb2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC650813 | View Product |
| Adenovirus | Transient expression | A650813 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG650813 | View Product |
| Gene knockout (non-viral) | PG650813 | View Product | |
| Gene knockout (AAV) | VG650813 | View Product | |
| CRISPR Activation | Gene activation | LA650813 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS650813 | View Product |
| Gene knockdown (AAV) | VS650813 | View Product | |
| ORF Vector | Template DNA | PC650813 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |