Anti-CD59 Antibody
Cat. No.
Y158048
Unit
100 μl
Price
$170.00
| Cat. No. | Y158048 |
| Name | Anti-CD59 Antibody |
| Clone | Polyclonal |
| Category | Polyclonal Antibodies |
| Gene Name | CD59 |
| Alias | 16.3A5, EJ16, EJ30, EL32, G344, p18-20 |
| Application | IHC,ELISA |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human,Mouse,Rat |
| Description | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | Rabbit polyclonal CD59 (1) antibody was raised against a recombinate human CD59 protein 29-102aa (BC001506). |
| Concentration | 100ug/100ul |
| Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
| Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human,Mouse,Rat |
| Specificity | Human and predicted against mouse and rat. |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our Anti-CD59 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y158048 |
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