Anti-CDKN2B Antibody
| Cat. No. | Y058684 |
| Name | Anti-CDKN2B Antibody |
| Clone | Polyclonal |
| Category | Polyclonal Antibodies |
| Gene Name | CDKN2B |
| Alias | P15, MTS2, INK4B, TP15, CDK4I, p15INK4b |
| Application | WB,IHC,ELISA |
| Application Info | For research use only Peptide ELISA titer: 1:10,000-1:40,000 Western blot analysis: 1:500-1:1,000 Immunohistochemistry: 1:100-1:500 Optimal dilutions/concentrations should be determined by the end use. |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human |
| Description | This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008] |
| Immunogen | Affinity purified |
| Concentration | 100ug/100ul |
| Recommended Dilutions | For research use only Peptide ELISA titer: 1:10,000-1:40,000 Western blot analysis: 1:500-1:1,000 Immunohistochemistry: 1:100-1:500 Optimal dilutions/concentrations should be determined by the end use. |
| Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
| Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our Anti-CDKN2B Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y058684 |
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