Anti-DUSP7 Antibody
| Cat. No. | Y058578 |
| Name | Anti-DUSP7 Antibody |
| Clone | Polyclonal |
| Category | Polyclonal Antibodies |
| Gene Name | DUSP7 |
| Alias | MKP-X, PYST2 |
| Application | WB,IHC,ELISA |
| Application Info | ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:500-1:1,000 Immunohistochemistry: 1:100-500 Optimal dilutions/concentrations should be determined by the end use |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human |
| Description | Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009] |
| Immunogen | Recombinant protein |
| Isotype | IgG |
| Concentration | 100ug/100ul |
| Recommended Dilutions | ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:500-1:1,000 Immunohistochemistry: 1:100-500 Optimal dilutions/concentrations should be determined by the end use |
| Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
| Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human |
| Specificity | Human |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our Anti-DUSP7 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y058578 |
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