Anti Human CDK4 Polyclonal Antibody
| Cat. No. | Y055114 |
| Name | Anti Human CDK4 Polyclonal Antibody |
| Clone | Polyclonal |
| Category | Polyclonal Antibodies |
| Gene Name | CDK4 |
| Alias | PSK-J3 |
| Application | WB,ELISA |
| Application Info | ELISA 1:1,000~100,000 Western blotting 1:100~1,000 |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human,Mouse |
| Description | The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant Protein |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Recommended Dilutions | ELISA 1:1,000~100,000 Western blotting 1:100~1,000 |
| Storage Buffer | PBS, pH 7.4 with 0.1% sodium azide, 50% Glycerol |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human,Mouse |
| Purity | Antigen Affinity Purified |
| Guarantee | abm guarantees that all our Anti Human CDK4 Polyclonal Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y055114 |
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