Anti-MBD2 Antibody
Cat. No.
Y058161
Unit
100 μl
Price
$170.00
| Cat. No. | Y058161 |
| Name | Anti-MBD2 Antibody |
| Clone | Polyclonal |
| Category | Polyclonal Antibodies |
| Gene Name | MBD2 |
| Application | WB,ELISA |
| Application Info | For research use only Peptide ELISA titer: 1:40,000-1:80,000 Western blot analysis: 1:200-500 Optimal dilutions/concentrations should be determined by the end use |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human,Mouse,Rat |
| Description | DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. |
| Immunogen | Synthetic peptide conjugated to KLH |
| Isotype | Rabbit IgG |
| Concentration | 100ug/100ul |
| Recommended Dilutions | For research use only Peptide ELISA titer: 1:40,000-1:80,000 Western blot analysis: 1:200-500 Optimal dilutions/concentrations should be determined by the end use |
| Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
| Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human,Mouse,Rat |
| Specificity | Not yet tested in other species. |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our Anti-MBD2 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y058161 |
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