Anti-MiTF Antibody
Cat. No.
Y300119
Unit
100 μl
Price
$232.00
| Cat. No. | Y300119 |
| Name | Anti-MiTF Antibody |
| Clone | Monoclonal |
| Category | Monoclonal Antibodies |
| Gene Name | MITF |
| Alias | WS2A, MI, bHLHe32 |
| Application | WB,IP |
| Application Info | WB: 1:250~1:1000. IP: Use at an assay dependent concentration. Optimal dilutions should be calculated by the end user based on their specific application. |
| Raised In | Mouse |
| Clonality | Monoclonal |
| Reactivity | Human |
| Description | The Microphthalmia-associated transcription factor or MiTF is encoded by the MITF gene. This transcription factor has a critical role in neural crest development and differentiation of neural crest derivatives. It is a transcription factor for tyrosinase and tyrosinase-related protein 1 and plays a critical role in the differentiation of various cell types as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. The MITF gene is important as it regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Diseases such as Waardenburg syndrome type 2 and Tietz syndrome are associated with heterozygous mutations in this gene. |
| Immunogen | Recombinant protein corresponding to human MiTF. |
| Isotype | IgG2b |
| Concentration | 100µg/100µl |
| Recommended Dilutions | WB: 1:250~1:1000. IP: Use at an assay dependent concentration. Optimal dilutions should be calculated by the end user based on their specific application. |
| Storage Buffer | PBS, pH 7.4 with 0.05% sodium azide |
| Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human |
| Specificity | Human MiTF. |
| Purity | The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography. |
| Guarantee | abm guarantees that all our Anti-MiTF Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y300119 |
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