PDE6B Antibody
| Cat. No. | Y058731 |
| Name | PDE6B Antibody |
| Clone | Polyclonal |
| Category | Polyclonal Antibodies |
| Gene Name | PDE6B |
| Alias | CSNB3, rd1, RP40 |
| Application | WB,IHC,ELISA |
| Application Info | For research use only ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:500-1:1,000 Immunohistochemistry: 1:100-1:500 Optimal dilutions/concentrations should be determined by the end use |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human |
| Description | Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009] |
| Immunogen | Affinity purified |
| Concentration | 100ug/100ul |
| Recommended Dilutions | For research use only ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:500-1:1,000 Immunohistochemistry: 1:100-1:500 Optimal dilutions/concentrations should be determined by the end use |
| Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
| Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our PDE6B Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y058731 |
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