HDAC2 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use HDAC2-specific vectors and viral particles designed for reliable HDAC2 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including HDAC2 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human HDAC2 Gene Overview
| Gene Name | histone deacetylase 2 |
|---|---|
| Gene Symbol | HDAC2 |
| Synonyms | HD2,RPD3,YAF1,KDAC2 |
| NCBI ID | 3066 |
| Ensembl ID | ENSG00000196591 |
| Uniprot ID | Q92769 |
| Gene Type | Protein coding |
Gene Summary
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
Human HDAC2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC123130 | View Product |
| AAV Vector & Virus | Long-term expression | VC123130 | View Product |
| Adenovirus | Transient expression | A123130 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG123130 | View Product |
| Gene knockout (non-viral) | PG123130 | View Product | |
| Gene knockout (AAV) | VG123130 | View Product | |
| CRISPR Activation | Gene activation | LA123130 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS123130 | View Product |
| Gene knockdown (AAV) | VS123130 | View Product | |
| ORF Vector | Template DNA | PC123130 | View Product |
Mouse Hdac2 Gene Overview
| Gene Name | histone deacetylase 2 |
|---|---|
| Gene Symbol | Hdac2 |
| Synonyms | YAF1,Yy1bp,mRPD3,D10Wsu179e |
| NCBI ID | 15182 |
| Ensembl ID | ENSMUSG00000019777 |
| Uniprot ID | P70288 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including DNA binding activity; Krueppel-associated box domain binding activity; and hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Involved in several processes, including circadian regulation of gene expression; eyelid development in camera-type eye; and negative regulation of DNA-templated transcription. Acts upstream of or within several processes, including cellular response to trichostatin A; nervous system development; and regulation of signal transduction. Located in heterochromatin; nucleus; and replication fork. Part of RNA polymerase II transcription repressor complex. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in stomach cancer. Orthologous to human HDAC2 (histone deacetylase 2). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Hdac2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC423130 | View Product |
| AAV Vector & Virus | Long-term expression | VC423130 | View Product |
| Adenovirus | Transient expression | A423130 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG423130 | View Product |
| Gene knockout (non-viral) | PG423130 | View Product | |
| Gene knockout (AAV) | VG423130 | View Product | |
| CRISPR Activation | Gene activation | LA423130 | View Product |
| siRNA Tools | Gene knockdown (AAV) | VS523130 | View Product |
| ORF Vector | Template DNA | PC423130 | View Product |
Rat Hdac2 Gene Overview
| Gene Name | histone deacetylase 2 |
|---|---|
| Gene Symbol | Hdac2 |
| Synonyms | |
| NCBI ID | 84577 |
| Ensembl ID | ENSRNOG00000000604 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including DNA-binding transcription factor binding activity; heat shock protein binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including behavioral response to ethanol; positive regulation of cell differentiation; and regulation of macromolecule metabolic process. Located in chromatin. Used to study Peyronie's disease; alcohol use disorder; and anxiety disorder. Biomarker of anxiety disorder; bronchitis; chronic obstructive pulmonary disease (multiple); endometriosis; and fetal alcohol spectrum disorder. Human ortholog(s) of this gene implicated in stomach cancer. Orthologous to human HDAC2 (histone deacetylase 2). [provided by Alliance of Genome Resources, Jul 2025]
Rat Hdac2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC623130 | View Product |
| AAV Vector & Virus | Long-term expression | VC623130 | View Product |
| Adenovirus | Transient expression | A623130 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG623130 | View Product |
| Gene knockout (non-viral) | PG623130 | View Product | |
| Gene knockout (AAV) | VG623130 | View Product | |
| CRISPR Activation | Gene activation | LA623130 | View Product |
| siRNA Tools | Gene knockdown (AAV) | VS623130 | View Product |
| ORF Vector | Template DNA | PC623130 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |